PEX10, peroxisomal biogenesis factor 10

PEX10, peroxisomal biogenesis factor 10

• This gene encodes a protein involved in import of peroxisomal matrix proteins. This protein localizes to the peroxisomal membrane. Mutations in this gene result in phenotypes within the Zellweger spectrum of peroxisomal biogenesis disorders, ranging from neonatal adrenoleukodystrophy to Zellweger syndrome. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

• Gene Synonyms (peroxisome biogenesis factor 10, RING finger protein 69, peroxin 10, peroxisome assembly protein 10, NALD, PBD6A, PBD6B, RNF69,)
• NCBI Gene ID: 5192
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R0A4
  UNIPROT ID#>>O60683
  UNIPROT ID#>>A0A024R068
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

peroxisomal biogenesis factor 10 interacts with:

• breast carcinoma amplified sequence 2
  BUB1, mitotic checkpoint serine/threonine kinase
  CD2-associated protein
  cell division cycle 26
  cell growth regulator with ring finger domain 1
  makorin ring finger protein 3
  peroxisomal biogenesis factor 10
  peroxisomal biogenesis factor 12
  peroxisomal biogenesis factor 14
  peroxisomal biogenesis factor 19
  peroxisomal biogenesis factor 2
  peroxisomal biogenesis factor 5
  phosphorylase kinase catalytic subunit gamma 2
  polycomb group ring finger 6
  sodium voltage-gated channel beta subunit 3
  torsin A interacting protein 1
  tripartite motif containing 25
  ubiquitin conjugating enzyme E2 I

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.