CDK3, cyclin dependent kinase 3

CDK3, cyclin dependent kinase 3

• This gene encodes a member of the cyclin-dependent protein kinase family. The protein promotes entry into S phase, in part by activating members of the E2F family of transcription factors. The protein also associates with cyclin C and phosphorylates the retinoblastoma 1 protein to promote exit from G0. [provided by RefSeq, Jul 2008]

• Gene Synonyms (cyclin-dependent kinase 3, cell division protein kinase 3,)
• NCBI Gene ID: 1018
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q00526
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

cyclin dependent kinase 3 interacts with:

• CDC28 protein kinase regulatory subunit 1B
  CDC28 protein kinase regulatory subunit 2
  Cdk5 and Abl enzyme substrate 1
  Cdk5 and Abl enzyme substrate 2
  cell division cycle 37, HSP90 cochaperone
  chromatin licensing and DNA replication factor 1
  COP9 signalosome subunit 5
  COP9 signalosome subunit 6
  cullin 1
  cyclin dependent kinase 3
  cyclin dependent kinase 5
  cyclin dependent kinase 5 regulatory subunit 1
  cyclin dependent kinase inhibitor 1A
  cyclin dependent kinase inhibitor 1B
  cyclin dependent kinase inhibitor 1C
  cyclin dependent kinase inhibitor 3
  cyclin E2
  cyclin I
  E2F transcription factor 1
  E2F transcription factor 2
  E2F transcription factor 3
  eukaryotic translation elongation factor 1 alpha 2
  eukaryotic translation initiation factor 2 alpha kinase 2
  fibroblast growth factor receptor substrate 2
  FKBP prolyl isomerase 5
  forkhead box P2
  geminin DNA replication inhibitor
  heat shock protein 90 alpha family class A member 1
  heat shock protein 90 alpha family class B member 1
  heat shock protein family A (Hsp70) member 1 like
  heat shock protein family A (Hsp70) member 4
  heat shock protein family A (Hsp70) member 8
  HEXIM P-TEFb complex subunit 1
  insulin like growth factor 1 receptor
  killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1
  La ribonucleoprotein 7, transcriptional regulator
  LIM homeobox 3
  LIM homeobox 4
  mesenchyme homeobox 2
  NEDD4 like E3 ubiquitin protein ligase
  negative elongation factor complex member A
  olfactory receptor family 2 subfamily G member 6
  orthodenticle homeobox 2
  paired box 5
  paired box 6
  paired box 8
  peroxisome proliferator activated receptor alpha
  progesterone receptor membrane component 1
  Rac GTPase activating protein 1
  RB transcriptional corepressor 1
  serine/threonine kinase 3
  serine/threonine kinase 4
  Smad nuclear interacting protein 1
  SNW domain containing 1
  speedy/RINGO cell cycle regulator family member E4
  S-phase kinase associated protein 1
  S-phase kinase associated protein 2
  STN1 subunit of CST complex
  stress induced phosphoprotein 1
  transcription factor Dp-1
  UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.