HSPA4, heat shock protein family A (Hsp70) member 4

HSPA4, heat shock protein family A (Hsp70) member 4

• Gene Synonyms (heat shock 70 kDa protein 4, epididymis secretory sperm binding protein Li 5a, heat shock 70-related protein APG-2, heat shock 70kD protein 4, heat shock 70kDa protein 4, heat shock protein, 110 kDa, hsp70 RY, APG-2, HEL-S-5a, HS24/P52, HSPH2, RY, hsp70, hsp70RY,)
• NCBI Gene ID: 3308
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P34932
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

heat shock protein family A (Hsp70) member 4 interacts with:

• 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1
  AAR2 splicing factor
  abraxas 1, BRCA1 A complex subunit
  adaptor related protein complex 1 subunit mu 1
  aminoacyl tRNA synthetase complex interacting multifunctional protein 2
  amyloid beta precursor protein binding protein 2
  angiotensin II receptor associated protein
  ankyrin repeat and SOCS box containing 9
  anterior gradient 2, protein disulphide isomerase family member
  apolipoprotein B mRNA editing enzyme catalytic subunit 3G
  aprataxin
  aryl hydrocarbon receptor interacting protein like 1
  ataxin 1
  ataxin 3
  autophagy related 16 like 1
  B cell linker
  BAG cochaperone 2
  BAG cochaperone 3
  BAG cochaperone 4
  BAG cochaperone 5
  BCL2 like 11
  BCL2 like 12
  BCL2-associated X protein
  BCL6 corepressor
  Bmi1 polycomb ring finger oncogene
  BRMS1 transcriptional repressor and anoikis regulator
  caseinolytic mitochondrial matrix peptidase proteolytic subunit
  catenin beta like 1
  CDK5 regulatory subunit associated protein 3
  cell division cycle 73
  chaperonin containing TCP1 subunit 2
  chromobox 2
  chromosome transmission fidelity factor 18
  cilia and flagella associated protein 52
  coiled-coil domain containing 117
  coiled-coil domain containing 8
  COP9 signalosome subunit 5
  copper metabolism domain containing 1
  CUE domain containing 2
  cullin 1
  cullin 3
  cullin 5
  cullin associated and neddylation dissociated 1
  cyclic GMP-AMP synthase
  cytosolic thiouridylase subunit 1
  DENN domain containing 2D
  denticleless E3 ubiquitin protein ligase homolog
  DNA damage induced apoptosis suppressor
  DNA damage inducible transcript 4
  DnaJ heat shock protein family (Hsp40) member A2
  DnaJ heat shock protein family (Hsp40) member A4
  DnaJ heat shock protein family (Hsp40) member B1
  DnaJ heat shock protein family (Hsp40) member B4
  DnaJ heat shock protein family (Hsp40) member B5
  DnaJ heat shock protein family (Hsp40) member B8
  DnaJ heat shock protein family (Hsp40) member C10
  DnaJ heat shock protein family (Hsp40) member C3
  DnaJ heat shock protein family (Hsp40) member C5
  DnaJ heat shock protein family (Hsp40) member C7
  dynamin 1 like
  dynamin binding protein
  egl-9 family hypoxia inducible factor 3
  elongation factor Tu GTP binding domain containing 2
  EPM2A glucan phosphatase, laforin
  ER lipid raft associated 2
  ezrin
  family with sequence similarity 114 member A1
  Fas associated factor 1
  F-box and WD repeat domain containing 8
  FUN14 domain containing 1
  G3BP stress granule assembly factor 1
  glutamate rich WD repeat containing 1
  GrpE like 1, mitochondrial
  GrpE like 2, mitochondrial
  H3 clustered histone 6
  heat shock protein 90 alpha family class A member 1
  heat shock protein 90 alpha family class B member 1
  heat shock protein family A (Hsp70) member 5
  heat shock protein family A (Hsp70) member 8
  heat shock protein family A (Hsp70) member 9
  heat shock protein family B (small) member 1
  heat shock protein family D (Hsp60) member 1
  heat shock protein family E (Hsp10) member 1
  heat shock protein family H (Hsp110) member 1
  HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
  heparanase
  HEXIM P-TEFb complex subunit 1
  histone deacetylase 3
  histone deacetylase 5
  histone deacetylase 6
  histone deacetylase 8
  HOP homeobox
  HSPA (Hsp70) binding protein 1
  huntingtin associated protein 1
  inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
  insulin receptor substrate 4
  interleukin 1 receptor associated kinase 1
  ISG15 ubiquitin like modifier
  jumonji domain containing 6, arginine demethylase and lysine hydroxylase
  junction plakoglobin
  karyopherin subunit alpha 1
  karyopherin subunit alpha 2
  keratin 18
  kinase suppressor of ras 1
  La ribonucleoprotein 7, transcriptional regulator
  leucine rich repeat kinase 2
  LIM domain kinase 1
  limb development membrane protein 1 like
  lin-37 DREAM MuvB core complex component
  lysine acetyltransferase 2B
  lysine acetyltransferase 6A
  lysine demethylase 4B
  lysine methyltransferase 5C
  lysyl-tRNA synthetase 1
  macroH2A.1 histone
  mahogunin ring finger 1
  McKusick-Kaufman syndrome
  MCL1 apoptosis regulator, BCL2 family member
  MDM2 proto-oncogene
  membrane bound O-acyltransferase domain containing 1
  membrane metalloendopeptidase
  menin 1
  MET proto-oncogene, receptor tyrosine kinase
  methylphosphate capping enzyme
  methyltransferase like 18
  methyltransferase like 21A
  methyltransferase like 3
  microtubule affinity regulating kinase 4
  microtubule associated protein tau
  mitogen-activated protein kinase 6
  mitogen-activated protein kinase 7
  mitogen-activated protein kinase kinase kinase 11
  mitogen-activated protein kinase kinase kinase 3
  mitogen-activated protein kinase kinase kinase 5
  moesin
  mortality factor 4 like 1
  mortality factor 4 like 2
  Mov10 RISC complex RNA helicase
  MRG domain binding protein
  mucin 1, cell surface associated
  MYC proto-oncogene, bHLH transcription factor
  myocardin
  myocilin
  NADPH oxidase 5
  N-alpha-acetyltransferase 10, NatA catalytic subunit
  NEDD8 ubiquitin like modifier
  negative regulator of ubiquitin like proteins 1
  neurofibromin 2
  neurotrophic receptor tyrosine kinase 1
  NHL repeat containing E3 ubiquitin protein ligase 1
  nibrin
  nitric oxide synthase 1
  nitric oxide synthase 2
  NLR family pyrin domain containing 12
  N-myc downstream regulated 1
  nuclear factor kappa B subunit 1
  nuclear receptor corepressor 1
  nuclear receptor subfamily 1 group I member 3
  nuclear receptor subfamily 2 group C member 2
  nuclear receptor subfamily 3 group C member 2
  nuclear RNA export factor 1
  nuclear transcription factor, X-box binding 1
  nucleophosmin 1
  Obg like ATPase 1
  OFD1 centriole and centriolar satellite protein
  opioid receptor delta 1
  OTU deubiquitinase, ubiquitin aldehyde binding 1
  oxidized low density lipoprotein receptor 1
  par-6 family cell polarity regulator gamma
  parkin coregulated
  parkin RBR E3 ubiquitin protein ligase
  Parkinsonism associated deglycase
  peroxiredoxin 3
  peroxiredoxin 4
  PH domain and leucine rich repeat protein phosphatase 2
  PHD finger protein 1
  phosphoethanolamine/phosphocholine phosphatase 1
  phosphoribosyl pyrophosphate amidotransferase
  phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
  PIH1 domain containing 1
  Pim-1 proto-oncogene, serine/threonine kinase
  pleckstrin homology domain containing A4
  pleckstrin homology like domain family A member 1
  polo like kinase 1
  poly(A) binding protein nuclear 1
  polycomb group ring finger 1
  potassium inwardly rectifying channel subfamily J member 10
  potassium voltage-gated channel subfamily D member 3
  potassium voltage-gated channel subfamily H member 2
  potassium voltage-gated channel subfamily Q member 1
  POU class 6 homeobox 2
  pre-mRNA processing factor 8
  prion protein
  prohibitin
  proliferation-associated 2G4
  proliferation-associated 2G4
  prolyl endopeptidase
  prostaglandin-endoperoxide synthase 2
  proteasome 26S subunit, ATPase 2
  proteasome 26S subunit, non-ATPase 10
  proteasome 26S subunit, non-ATPase 4
  proteasome subunit alpha 2
  protein kinase AMP-activated catalytic subunit alpha 1
  protein kinase C beta
  protein kinase C delta
  protein kinase C gamma
  protein kinase cAMP-activated catalytic subunit alpha
  protein phosphatase 1 catalytic subunit alpha
  protein phosphatase 1 catalytic subunit beta
  protein phosphatase 1 catalytic subunit gamma
  protein phosphatase 1 regulatory subunit 10
  protein phosphatase 5 catalytic subunit
  protein phosphatase 6 regulatory subunit 1
  protein phosphatase, Mg2+/Mn2+ dependent 1G
  protein tyrosine phosphatase non-receptor type 23
  protein tyrosine phosphatase receptor type R
  PTEN induced kinase 1
  pyrroline-5-carboxylate reductase 2
  RAB29, member RAS oncogene family
  RAD52 homolog, DNA repair protein
  radixin
  Raf-1 proto-oncogene, serine/threonine kinase
  RAN binding protein 6
  RAP1A, member of RAS oncogene family
  RB binding protein 6, ubiquitin ligase
  receptor interacting serine/threonine kinase 4
  RecQ like helicase 4
  regulatory associated protein of MTOR complex 1
  REL proto-oncogene, NF-kB subunit
  RELA proto-oncogene, NF-kB subunit
  REST corepressor 1
  rhodopsin
  ribonucleotide reductase regulatory subunit M2
  ribosomal protein S3
  ribosomal protein SA
  ring finger and CCCH-type domains 1
  ring finger and CCCH-type domains 2
  ring-box 1
  RNA polymerase II associated protein 3
  Ro60, Y RNA binding protein
  RPTOR independent companion of MTOR complex 2
  RuvB like AAA ATPase 1
  salt inducible kinase 2
  Sec23 homolog A, COPII coat complex component
  SEC23 interacting protein
  selenoprotein S
  sequestosome 1
  serine hydroxymethyltransferase 2
  serine protease 23
  serine/threonine kinase 40
  serum/glucocorticoid regulated kinase 1
  SGT1 homolog, MIS12 kinetochore complex assembly cochaperone
  signal regulatory protein alpha
  sirtuin 1
  sirtuin 3
  sirtuin 7
  slingshot protein phosphatase 1
  SMAD family member 2
  SMAD family member 3
  small glutamine rich tetratricopeptide repeat containing alpha
  small nuclear ribonucleoprotein polypeptide E
  SMG1 nonsense mediated mRNA decay associated PI3K related kinase
  snail family transcriptional repressor 1
  sodium channel and clathrin linker 1
  solute carrier family 12, member 3
  solute carrier family 2 member 14
  solute carrier family 2 member 3
  solute carrier family 27 member 3
  solute carrier family 9 member A1
  somatostatin receptor 3
  sorting nexin 20
  squamous cell carcinoma antigen recognized by T cells 3
  ST13 Hsp70 interacting protein
  STIP1 homology and U-box containing protein 1
  STIP1 homology and U-Box containing protein 1
  stress induced phosphoprotein 1
  succinate dehydrogenase complex flavoprotein subunit A
  superoxide dismutase 1
  synuclein alpha
  TAR DNA binding protein
  t-complex 1
  TEA domain transcription factor 3
  TELO2 interacting protein 1
  TELO2 interacting protein 2
  telomerase reverse transcriptase
  telomere maintenance 2
  telomeric repeat binding factor 1
  telomeric repeat binding factor 2
  TERF2 interacting protein
  testis specific serine kinase 6
  tetratricopeptide repeat domain 1
  tetratricopeptide repeat domain 3
  tetratricopeptide repeat domain 9B
  thioredoxin domain containing 5
  thyroid hormone receptor alpha
  thyroid hormone receptor beta
  titin-cap
  TNF receptor associated factor 6
  TNFAIP3 interacting protein 2
  toll like receptor 4
  toll like receptor 9
  TOX high mobility group box family member 4
  TP53 regulated inhibitor of apoptosis 1
  TRAF3 interacting protein 2
  transcription factor 7 like 2
  transcription factor CP2
  transforming growth factor beta receptor 1
  transgelin 2
  transgelin 3
  translocase of outer mitochondrial membrane 40
  tripartite motif containing 25
  tripartite motif containing 32
  tripartite motif containing 63
  tRNA methyltransferase 12 homolog
  tubulin beta class I
  tubulin gamma 1
  tumor protein p53
  tumor protein p53 binding protein 2
  tumor protein p73
  tyrosinase related protein 1
  ubiquilin 2
  ubiquitin conjugating enzyme E2 L3
  ubiquitin conjugating enzyme E2 M
  ubiquitin interaction motif containing 1
  ubiquitin like 4A
  ubiquitin protein ligase E3A
  ubiquitin specific peptidase 19
  ubiquitin specific peptidase 39
  unk zinc finger
  valosin containing protein
  vascular endothelial growth factor A
  vir like m6A methyltransferase associated
  von Hippel-Lindau tumor suppressor
  VRK serine/threonine kinase 1
  VRK serine/threonine kinase 3
  WD repeat domain 82
  WT1 transcription factor
  WW domain containing oxidoreductase
  X-ray repair cross complementing 5
  Yes1 associated transcriptional regulator
  YY1 transcription factor
  zeta chain of T cell receptor associated protein kinase 70
  ZFP36 ring finger protein
  zinc finger MYM-type containing 2
  zinc finger MYND-type containing 19
  zw10 kinetochore protein

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.