FER, FER tyrosine kinase

FER, FER tyrosine kinase

• The protein encoded by this gene is a member of the FPS/FES family of non-transmembrane receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome X. [provided by RefSeq, Apr 2015]

• Gene Synonyms (PPP1R74, TYK3, p94-Fer, tyrosine-protein kinase Fer, feline encephalitis virus-related kinase FER, fer (fps/fes related) tyrosine kinase, fujinami poultry sarcoma/Feline sarcoma-related protein Fer, phosphoprotein NCP94, protein phosphatase 1, regulatory subunit 74, proto-oncogene c-Fer, tyrosine kinase 3,)
• NCBI Gene ID: 2241
• Species: Homo sapiens (Human)
• UNIPROT ID#>>W0S1B5
  UNIPROT ID#>>P16591
  UNIPROT ID#>>Q6PEJ9
  UNIPROT ID#>>W0S0X4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

FER tyrosine kinase interacts with:

• activity regulated cytoskeleton associated protein
  cell division cycle 37, HSP90 cochaperone
  dynamin 3
  FER tyrosine kinase
  heat shock protein 90 alpha family class A member 1
  insulin receptor substrate 1
  Janus kinase 1
  junction plakoglobin
  LIM domain and actin binding 1
  nuclear RNA export factor 1
  phosphoinositide-3-kinase regulatory subunit 1
  phosphoinositide-3-kinase regulatory subunit 3
  potassium channel tetramerization domain containing 4
  protein phosphatase 1 regulatory subunit 7
  signal transducer and activator of transcription 3
  TATA element modulatory factor 1
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.