GNB2, G protein subunit beta 2

GNB2, G protein subunit beta 2

• Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. This gene contains a trinucleotide (CCG) repeat length polymorphism in its 5' UTR. [provided by RefSeq, Jul 2008]

• Gene Synonyms (guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2, G protein, beta-2 subunit, epididymis secretory sperm binding protein, g protein subunit beta-2, guanine nucleotide binding protein (G protein), beta polypeptide 2, guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 2, signal-transducing guanine nucleotide-binding regulatory protein beta subunit, transducin beta chain 2,)
• NCBI Gene ID: 2783
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P62879
  UNIPROT ID#>>Q6FHM2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

G protein subunit beta 2 interacts with:

• 5-hydroxytryptamine receptor 2C
  acyl-CoA synthetase family member 2
  ADAM metallopeptidase domain 21
  aldo-keto reductase family 7 member A3
  angiopoietin like 7
  ankyrin repeat and SOCS box containing 6
  anterior gradient 2, protein disulphide isomerase family member
  ataxin 10
  ATPase H+ transporting V0 subunit d1
  autophagy related 16 like 1
  bone morphogenetic protein receptor, type 1A
  centrosomal protein 76
  cerebellin 4 precursor
  chaperonin containing TCP1 subunit 2
  chaperonin containing TCP1 subunit 3
  chaperonin containing TCP1 subunit 4
  chaperonin containing TCP1 subunit 6B
  chaperonin containing Tcp1, subunit 2 (beta)
  chaperonin containing Tcp1, subunit 3 (gamma)
  chaperonin containing Tcp1, subunit 4 (delta)
  chitinase acidic
  chromobox 1
  complexin 3
  cullin 4A
  cyclic GMP-AMP synthase
  cyclin dependent kinase 13
  cyclin-dependent kinase 1
  cytochrome c oxidase assembly factor COX14
  defensin beta 104A
  dynein light chain Tctex-type 1
  eukaryotic translation initiation factor 3 subunit L
  exportin 1
  family with sequence similarity 118 member B
  F-box and leucine rich repeat protein 14
  G protein subunit gamma 10
  G protein subunit gamma 12
  G protein subunit gamma 13
  G protein subunit gamma 2
  G protein subunit gamma 3
  G protein subunit gamma 4
  G protein subunit gamma 5
  G protein subunit gamma 7
  G protein subunit gamma 8
  G protein subunit gamma transducin 1
  G protein subunit gamma transducin 2
  G3BP stress granule assembly factor 1
  glycogen synthase kinase 3 beta
  granulin precursor
  growth factor receptor bound protein 7
  H2B clustered histone 21
  H4 histone 16
  HAUS augmin-like complex, subunit 1
  HAUS augmin-like complex, subunit 4
  heme oxygenase 2
  histone deacetylase 5
  hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
  inhibitor of DNA binding 3, HLH protein
  insulin like growth factor binding protein 1
  interleukin 27 receptor subunit alpha
  KRAS proto-oncogene, GTPase
  LDL receptor related protein 1
  matrix metallopeptidase 26
  MAU2 sister chromatid cohesion factor
  melatonin receptor 1B
  microsomal glutathione S-transferase 1
  MYC proto-oncogene, bHLH transcription factor
  myocyte enhancer factor 2A
  myosin heavy chain 9
  myosin XIX
  myosin, heavy polypeptide 10, non-muscle
  myotubularin related protein 7
  N-acetyltransferase 16 (putative)
  NADH:ubiquinone oxidoreductase core subunit S1
  neurotrophic receptor tyrosine kinase 3
  nuclear factor of activated T cells 2
  nuclear receptor subfamily 3 group C member 1
  phosducin like
  phospholipase A2 group X
  phosphomannomutase 1
  pleckstrin homology domain containing A4
  poly(A) specific ribonuclease subunit PAN2
  poly(ADP-ribose) polymerase family member 12
  poly(rC) binding protein 1
  potassium channel tetramerisation domain containing 5
  potassium inwardly rectifying channel subfamily J member 5
  PRAME family member 17
  prefoldin subunit 1
  prefoldin subunit 4
  prefoldin subunit 5
  prefoldin subunit 6
  protein O-mannose kinase
  protein phosphatase 1 catalytic subunit gamma
  proton activated chloride channel 1
  pyruvate carboxylase
  pyruvate dehydrogenase E1 subunit beta
  RAB7A, member RAS oncogene family
  RAD18 E3 ubiquitin protein ligase
  Raf-1 proto-oncogene, serine/threonine kinase
  RASD family member 2
  regulator of G protein signaling 6
  RNA polymerase III subunit E
  Scm polycomb group protein homolog 1
  serine incorporator 1
  sex hormone binding globulin
  shugoshin 2
  signal transducer and activator of transcription 1
  signal transducer and activator of transcription 3
  signal transducer and activator of transcription 5A
  small nuclear ribonucleoprotein U1 subunit 70
  solute carrier family 4 member 8
  solute carrier family 6 member 5
  Sp6 transcription factor
  synaptopodin
  TAR DNA binding protein
  TATA-box binding protein
  TATA-box binding protein associated factor 8
  t-complex 1
  tectonic family member 1
  thioredoxin domain containing 9
  TNFAIP3 interacting protein 2
  transcription factor CP2
  transforming growth factor beta receptor 1
  transmembrane serine protease 12
  tripartite motif containing 28
  tripartite motif-containing 69
  tropomodulin 3
  tropomyosin 1, alpha
  TSC22 domain family member 1
  tubulin gamma 1
  tubulointerstitial nephritis antigen like 1
  tumor protein p53
  ubiquitin C
  ubiquitin specific peptidase 50
  UFM1 specific ligase 1
  USO1 vesicle docking factor
  VHL binding protein 1
  voltage dependent anion channel 1
  voltage dependent anion channel 2
  voltage dependent anion channel 3
  WD repeat containing, antisense to TP73
  Yes1 associated transcriptional regulator
  zinc finger protein 212
  zinc finger protein 517

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.