HNRNPH2, heterogeneous nuclear ribonucleoprotein H2

HNRNPH2, heterogeneous nuclear ribonucleoprotein H2

• This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that binds to RNAs. It is very similar to the family member HNRPH1. This gene is thought to be involved in Fabray disease and X-linked agammaglobulinemia phenotype. Alternative splicing results in multiple transcript variants encoding the same protein. Read-through transcription between this locus and the ribosomal protein L36a gene has been observed. [provided by RefSeq, Jan 2011]

• Gene Synonyms (heterogeneous nuclear ribonucleoprotein H2, FTP-3, epididymis secretory sperm binding protein, heterogeneous nuclear ribonucleoprotein H-prime, heterogeneous nuclear ribonucleoprotein H2 (H'), hnRNP H', hnRNP H2, FTP3, HNRPH', HNRPH2, MRXSB, NRPH2, hnRNPH',)
• NCBI Gene ID: 3188
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P55795
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

heterogeneous nuclear ribonucleoprotein H2 interacts with:

• 3-hydroxyisobutyryl-CoA hydrolase
  AAR2 splicing factor
  apolipoprotein B mRNA editing enzyme catalytic subunit 3B
  chloride intracellular channel 4
  chromosome 19 open reading frame 25
  COP9 signalosome subunit 5
  COP9 signalosome subunit 6
  cullin 1
  cullin 2
  cullin 3
  cullin 4B
  cullin 5
  cullin 7
  cullin associated and neddylation dissociated 1
  cyclin K
  decapping enzyme, scavenger
  defective in cullin neddylation 1 domain containing 1
  elongation factor Tu GTP binding domain containing 2
  embryonic ectoderm development
  enhancer of polycomb homolog 2
  eukaryotic translation initiation factor 4A3
  family with sequence similarity 120A
  Fas activated serine/threonine kinase
  F-box and WD repeat domain containing 11
  F-box protein 6
  F-box protein 7
  G3BP stress granule assembly factor 1
  glutamine and serine rich 1
  GPN-loop GTPase 1
  H4 clustered histone 1
  heat shock protein family A (Hsp70) member 5
  heat shock protein family B (small) member 1
  heat shock transcription factor 2 binding protein
  heterogeneous nuclear ribonucleoprotein A0
  heterogeneous nuclear ribonucleoprotein A1 like 2
  heterogeneous nuclear ribonucleoprotein A3
  heterogeneous nuclear ribonucleoprotein D like
  heterogeneous nuclear ribonucleoprotein F
  heterogeneous nuclear ribonucleoprotein H2
  heterogeneous nuclear ribonucleoprotein H3
  heterogeneous nuclear ribonucleoprotein K
  heterogeneous nuclear ribonucleoprotein M
  heterogeneous nuclear ribonucleoprotein U like 1
  heterogeneous nuclear ribonucleoprotein U like 2
  HEXIM P-TEFb complex subunit 1
  histone deacetylase 5
  inositol-3-phosphate synthase 1
  integrin alpha FG-GAP repeat containing 1
  interleukin enhancer binding factor 3
  isoleucyl-tRNA synthetase 2, mitochondrial
  La ribonucleoprotein 7, transcriptional regulator
  legumain
  MAGE family member A3
  mago homolog, exon junction complex subunit
  MAK16 homolog
  matrin 3
  methylphosphate capping enzyme
  minichromosome maintenance complex component 2
  minichromosome maintenance complex component 3
  Mov10 RISC complex RNA helicase
  musashi RNA binding protein 1
  musashi RNA binding protein 2
  muscleblind like splicing regulator 1
  MYC associated factor X
  MYC proto-oncogene, bHLH transcription factor
  Nanog homeobox
  NEDD8 ubiquitin like modifier
  ninein like
  nuclear receptor subfamily 2 group C member 2
  nudix hydrolase 16 like 1
  obscurin like cytoskeletal adaptor 1
  palmitoyl-protein thioesterase 1
  pleckstrin homology domain containing A4
  polyglutamine binding protein 1
  pre-mRNA processing factor 31
  pre-mRNA processing factor 8
  procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
  procollagen-lysine,2-oxoglutarate 5-dioxygenase 2
  procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
  programmed cell death 6
  prohibitin
  prolylcarboxypeptidase
  proteasome 20S subunit alpha 3
  proteasome 26S subunit, non-ATPase 14
  protein arginine methyltransferase 6
  protein kinase D2
  protein kinase N3
  PTEN induced kinase 1
  pyrroline-5-carboxylate reductase 1
  QKI, KH domain containing RNA binding
  RAD21 cohesin complex component
  receptor for activated C kinase 1
  RecQ like helicase 4
  ring finger and CCCH-type domains 1
  ring finger and CCCH-type domains 2
  RIO kinase 1
  RNA binding fox-1 homolog 2
  RNA binding motif protein 10
  RNA binding motif protein 12B
  RNA binding motif protein 39
  RNA binding motif protein 4
  RNA binding motif protein X-linked
  RUN and SH3 domain containing 1
  SMAD specific E3 ubiquitin protein ligase 1
  small nuclear ribonucleoprotein polypeptide C
  small nuclear ribonucleoprotein U1 subunit 70
  splicing factor 1
  SRSF protein kinase 2
  staufen double-stranded RNA binding protein 1
  synaptotagmin binding cytoplasmic RNA interacting protein
  TAR DNA binding protein
  tektin 1
  TNFAIP3 interacting protein 2
  tripartite motif containing 28
  tyrosine kinase non receptor 1
  tyrosyl-tRNA synthetase 1
  ubiquitin associated and SH3 domain containing B
  ubiquitin C-terminal hydrolase L3
  ubiquitin like 4A
  valosin containing protein
  vir like m6A methyltransferase associated
  von Hippel-Lindau tumor suppressor
  WD repeat domain 77
  WD repeat domain 83
  zinc finger SWIM-type containing 5

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.