LMNB1, lamin B1

LMNB1, lamin B1

• This gene encodes one of the two B-type lamin proteins and is a component of the nuclear lamina. A duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

• Gene Synonyms (ADLD, LMN, LMN2, LMNB, lamin-B1,)
• NCBI Gene ID: 4001
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P20700
  UNIPROT ID#>>B4DZT3
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

lamin B1 interacts with:

• actin related protein 10
  actin related protein 1A
  actin related protein 1B
  AKT interacting protein
  anterior gradient 2, protein disulphide isomerase family member
  ataxia telangiectasia mutated
  ATP binding cassette subfamily E member 1
  ATP binding cassette subfamily G member 8
  autophagy related 16 like 1
  centromere protein H
  checkpoint kinase 2
  chromobox 2
  chromosome 17 open reading frame 49
  coiled-coil domain containing 8
  coiled-coil domain containing 88B
  cullin 7
  decapping enzyme, scavenger
  DExD-box helicase 21
  DNA methyltransferase 1 associated protein 1
  dynactin subunit 2
  dynactin subunit 3
  embryonic ectoderm development
  family with sequence similarity 169 member A
  F-box protein 6
  GABA type A receptor-associated protein
  GIT ArfGAP 2
  H4 clustered histone 1
  HECT and RLD domain containing E3 ubiquitin protein ligase 2
  HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
  heterochromatin protein 1 binding protein 3
  heterogeneous nuclear ribonucleoprotein F
  heterogeneous nuclear ribonucleoprotein M
  karyopherin subunit alpha 6
  lamin A
  lamin B1
  lamin B2
  leucine rich repeat kinase 2
  limb development membrane protein 1 like
  magnesium transporter 1
  MAP3K12 binding inhibitory protein 1
  maternal embryonic leucine zipper kinase
  meiosis 1 associated protein
  metal regulatory transcription factor 1
  methyltransferase like 14
  microtubule associated protein 1 light chain 3 alpha
  microtubule associated protein 1 light chain 3 beta
  microtubule associated protein 1 light chain 3 gamma
  minichromosome maintenance complex component 2
  MYC proto-oncogene, bHLH transcription factor
  nestin
  neurotrophic receptor tyrosine kinase 1
  nicastrin
  nicastrin
  ninein
  NK2 homeobox 1
  non-SMC condensin I complex subunit H
  nuclear receptor subfamily 2 group C member 2
  nudE neurodevelopment protein 1 like 1
  obscurin like cytoskeletal adaptor 1
  parkin RBR E3 ubiquitin protein ligase
  peripherin
  PIH1 domain containing 2
  pleckstrin homology domain containing A4
  plectin
  polycomb group ring finger 2
  polyhomeotic homolog 3
  potassium channel tetramerization domain containing 10
  POU class 2 homeobox 1
  protein inhibitor of activated STAT 2
  protein kinase C alpha
  protein kinase C beta
  protein kinase C delta
  protein phosphatase 1 regulatory subunit 13B
  PTEN induced kinase 1
  pyruvate dehydrogenase E1 subunit alpha 1
  Rac family small GTPase 1
  RAD51 recombinase
  RE1 silencing transcription factor
  RecQ like helicase 4
  replication protein A1
  replication protein A3
  retinoid X receptor alpha
  ring finger protein 123
  ring finger protein 13
  ring finger protein 4
  ring-box 1
  serine and arginine rich splicing factor 6
  small ubiquitin like modifier 4
  SNAP associated protein
  spartin
  spectrin alpha, non-erythrocytic 1
  splicing factor 3b subunit 3
  SprT-like N-terminal domain
  SRSF protein kinase 2
  staufen double-stranded RNA binding protein 1
  succinate dehydrogenase complex flavoprotein subunit A
  SUMO specific peptidase 2
  superoxide dismutase 1
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
  thymopoietin
  TNFAIP3 interacting protein 2
  torsin 1A interacting protein 1
  transcription factor CP2
  transmembrane protein 41B
  transmembrane protein 63B
  tumor protein p53 binding protein 2
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
  ubiquitin C
  ubiquitin conjugating enzyme E2 I
  ubiquitin conjugating enzyme E2 M
  ubiquitin C-terminal hydrolase L3
  URB2 ribosome biogenesis homolog
  vascular cell adhesion molecule 1
  vimentin
  vir like m6A methyltransferase associated
  voltage dependent anion channel 1
  Yes1 associated transcriptional regulator
  zinc finger protein 598, E3 ubiquitin ligase
  zinc finger ZZ-type and EF-hand domain containing 1
  ZW10 interacting kinetochore protein

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.