MAFG, MAF bZIP transcription factor G

MAFG, MAF bZIP transcription factor G

• Globin gene expression is regulated through nuclear factor erythroid-2 (NFE2) elements located in enhancer-like locus control regions positioned many kb upstream of alpha- and beta-gene clusters (summarized by Blank et al., 1997 [PubMed 9166829]). NFE2 DNA-binding activity consists of a heterodimer containing a ubiquitous small Maf protein (MafF, MIM 604877; MafG; or MafK, MIM 600197) and the tissue-restricted protein p45 NFE2 (MIM 601490). Both subunits are members of the activator protein-1-like superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160).[supplied by OMIM, Mar 2010]

• Gene Synonyms (hMAF, transcription factor MafG, basic leucine zipper transcription factor MafG, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G,)
• NCBI Gene ID: 4097
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R8X1
  UNIPROT ID#>>O15525
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

MAF bZIP transcription factor G interacts with:

• basic leucine zipper ATF-like transcription factor 3
  BTB and CNC homology 1, basic leucine zipper transcription factor 1
  BTB domain and CNC homolog 2
  chromodomain helicase DNA binding protein 8
  deuterosome assembly protein 1
  general transcription factor IIA subunit 1 like
  H4 clustered histone 1
  homeobox and leucine zipper encoding
  MAF bZIP transcription factor F
  MAF bZIP transcription factor G
  mediator complex subunit 31
  mitogen-activated protein kinase 3
  nuclear factor of activated T cells 2
  nuclear factor, erythroid 2
  nuclear factor, erythroid 2 like 1
  nuclear factor, erythroid 2 like 2
  nuclear factor, erythroid 2 like 3
  nuclear factor, interleukin 3 regulated
  p53-induced death domain protein 1
  paired box 6
  paired related homeobox 1
  protein phosphatase 1 catalytic subunit alpha
  RNA binding motif protein 48
  small nuclear ribonucleoprotein polypeptide N
  vimentin

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.