MYH10, myosin heavy chain 10

MYH10, myosin heavy chain 10

• This gene encodes a member of the myosin superfamily. The protein represents a conventional non-muscle myosin; it should not be confused with the unconventional myosin-10 (MYO10). Myosins are actin-dependent motor proteins with diverse functions including regulation of cytokinesis, cell motility, and cell polarity. Mutations in this gene have been associated with May-Hegglin anomaly and developmental defects in brain and heart. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

• Gene Synonyms (NMMHC-IIB, NMMHCB, myosin-10, cellular myosin heavy chain, type B, myosin heavy chain, nonmuscle type B, myosin, heavy chain 10, non-muscle, myosin, heavy polypeptide 10, non-muscle, nonmuscle myosin II heavy chain-B, nonmuscle myosin heavy chain IIB,)
• NCBI Gene ID: 4628
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P35580
  UNIPROT ID#>>G1UI33
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

myosin heavy chain 10 interacts with:

• Aly/REF export factor
  ankyrin repeat and SOCS box containing 12
  anterior gradient 2, protein disulphide isomerase family member
  argonaute RISC catalytic component 2
  armadillo repeat containing 12
  aurora kinase A interacting protein 1
  B cell receptor associated protein 31
  CCCTC-binding factor
  cullin 1
  decapping enzyme, scavenger
  DExD-box helicase 39B
  Ecm29 proteasome adaptor and scaffold
  elongation factor Tu GTP binding domain containing 2
  embryonic ectoderm development
  eukaryotic translation initiation factor 4A3
  extended synaptotagmin 1
  F-box protein 25
  forkhead box P1
  H2A clustered histone 4
  H3 clustered histone 1
  H4 clustered histone 1
  heterogeneous nuclear ribonucleoprotein M
  histone deacetylase 6
  hook microtubule tethering protein 3
  inhibitor of nuclear factor kappa B kinase subunit epsilon
  IQ motif containing GTPase activating protein 1
  kinesin family member 7
  leucine rich repeat containing G protein-coupled receptor 4
  listerin E3 ubiquitin protein ligase 1
  mediator complex subunit 9
  microtubule affinity regulating kinase 4
  myosin IC
  myosin light chain 3
  myosin light chain 6
  myosin XIX
  neurotrophic receptor tyrosine kinase 1
  nuclear receptor subfamily 2 group C member 2
  p21 (RAC1) activated kinase 2
  PBX homeobox 1
  phosphatase and tensin homolog
  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
  phosphoinositide-3-kinase regulatory subunit 2
  pleckstrin homology domain containing A4
  poly(A) specific ribonuclease subunit PAN2
  prohibitin
  proteasome 20S subunit alpha 1
  protein kinase AMP-activated non-catalytic subunit beta 1
  protein phosphatase 2 catalytic subunit beta
  prothymosin alpha
  PTEN induced kinase 1
  RAB11A, member RAS oncogene family
  RAD18 E3 ubiquitin protein ligase
  RAS like proto-oncogene A
  replication protein A1
  replication protein A2
  replication protein A3
  S100 calcium binding protein A4
  SHC adaptor protein 1
  single stranded DNA binding protein 1
  sirtuin 7
  slingshot protein phosphatase 1
  small nuclear ribonucleoprotein U1 subunit 70
  snail family transcriptional repressor 1
  Sp1 transcription factor
  spindle apparatus coiled-coil protein 1
  staufen double-stranded RNA binding protein 1
  tectonin beta-propeller repeat containing 2
  telomeric repeat binding factor 2
  tet methylcytosine dioxygenase 2
  thymopoietin
  TNF receptor superfamily member 10d
  TNFAIP3 interacting protein 2
  transcription factor CP2
  tripartite motif containing 25
  tripartite motif-containing 59
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
  ubiquitin associated and SH3 domain containing B
  ubiquitin conjugating enzyme E2 M
  ubiquitin specific peptidase 45
  vascular cell adhesion molecule 1
  vir like m6A methyltransferase associated
  WD repeat domain 76
  WD repeat domain 77
  Yes1 associated transcriptional regulator
  zinc finger FYVE-type containing 21
  zinc finger protein 512B
  zinc finger protein 598, E3 ubiquitin ligase

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.