NONO, non-POU domain containing octamer binding

NONO, non-POU domain containing octamer binding

• This gene encodes an RNA-binding protein which plays various roles in the nucleus, including transcriptional regulation and RNA splicing. A rearrangement between this gene and the transcription factor E3 gene has been observed in papillary renal cell carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes exist on Chromosomes 2 and 16. [provided by RefSeq, Feb 2009]

• Gene Synonyms (MRXS34, NMT55, NRB54, P54, P54NRB, PPP1R114, non-POU domain-containing octamer-binding protein, 54 kDa nuclear RNA- and DNA-binding protein, 55 kDa nuclear protein, DNA-binding p52/p100 complex, 52 kDa subunit, non-POU domain-containing octamer (ATGCAAAT) binding protein, p54(nrb), protein phosphatase 1, regulatory subunit 114,)
• NCBI Gene ID: 4841
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q15233
  UNIPROT ID#>>A0A0S2Z4Z9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

non-POU domain containing octamer binding interacts with:

• agmatinase
  aldehyde dehydrogenase 18 family member A1
  ankyrin repeat and SOCS box containing 18
  ankyrin repeat and SOCS box containing 3
  anterior gradient 2, protein disulphide isomerase family member
  antigen identified by monoclonal antibody Ki 67
  armadillo repeat containing 8
  autophagy related 16 like 1
  basic helix-loop-helix family member e41
  bromodomain containing 7
  BTB and CNC homology 1, basic leucine zipper transcription factor 1
  CCCTC-binding factor
  CD2 cytoplasmic tail binding protein 2
  checkpoint kinase 2
  chromatin assembly factor 1 subunit A
  chromosome 11 open reading frame 68
  cleavage and polyadenylation specific factor 6
  coiled-coil domain containing 22
  coiled-coil domain containing 8
  COP9 signalosome subunit 5
  cullin 2
  cullin 3
  cullin 4B
  cullin 7
  cullin associated and neddylation dissociated 1
  CXXC finger 1 (PHD domain)
  cytochrome c oxidase subunit 5A
  developmental pluripotency-associated 3
  DNA topoisomerase I
  dynein cytoplasmic 2 heavy chain 1
  ecdysoneless cell cycle regulator
  elongation factor Tu GTP binding domain containing 2
  embryonic ectoderm development
  exportin 1
  expressed sequence AI837181
  Fas associated factor 1
  F-box and WD repeat domain containing 7
  FMR1 autosomal homolog 2
  glycogenin 2
  golgi reassembly stacking protein 2
  H3.4 histone
  H4 clustered histone 1
  HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
  hes related family bHLH transcription factor with YRPW motif 1
  heterogeneous nuclear ribonucleoprotein A3
  HEXIM P-TEFb complex subunit 1
  histone deacetylase 3
  histone deacetylase 5
  histone deacetylase 6
  hyaluronan binding protein 4
  interleukin 1 receptor associated kinase 3
  iron-sulfur cluster assembly factor IBA57
  kinase suppressor of ras 1
  La ribonucleoprotein 7, transcriptional regulator
  LIM domain only 4
  lin-7 homolog C (C. elegans)
  mab-21 like 2
  matrin 3
  methylphosphate capping enzyme
  methyltransferase like 14
  methyltransferase like 3
  mitochondrial ribosomal protein L39
  mitochondrial ribosomal protein L41
  mitogen-activated protein kinase 13
  mitotic arrest deficient 1 like 1
  neurotrophic receptor tyrosine kinase 1
  NK2 homeobox 1
  non-POU domain containing octamer binding
  nuclear protein 1, transcriptional regulator
  nuclear receptor subfamily 2 group C member 1
  nuclear receptor subfamily 2 group C member 2
  nucleoporin 133
  nucleoporin 210
  obscurin like cytoskeletal adaptor 1
  origin recognition complex subunit 5
  OTU deubiquitinase 5
  paired like homeodomain 3
  paraspeckle component 1
  Parkinsonism associated deglycase
  peptidylprolyl cis/trans isomerase, NIMA-interacting 1
  PIH1 domain containing 1
  pleckstrin homology and FYVE domain containing 2
  pleckstrin homology domain containing A4
  PMS1 homolog 1, mismatch repair system component
  poly(A) specific ribonuclease subunit PAN2
  poly(rC) binding protein 1
  polymerase (RNA) II (DNA directed) polypeptide A
  polypyrimidine tract binding protein 1
  POP1 homolog, ribonuclease P/MRP subunit
  pre-mRNA processing factor 40 homolog A
  pre-mRNA processing factor 8
  prohibitin
  proliferating cell nuclear antigen
  proline and serine rich 1
  proteasome 20S subunit alpha 3
  protein kinase AMP-activated catalytic subunit alpha 2
  protein phosphatase 1 catalytic subunit alpha
  protein phosphatase 1 catalytic subunit beta
  protein phosphatase 1 catalytic subunit gamma
  PTEN induced kinase 1
  RAS like proto-oncogene A
  RAS like proto-oncogene B
  RE1 silencing transcription factor
  RecQ like helicase 4
  replication protein A1
  replication protein A2
  replication protein A3
  retinoid X receptor alpha
  retinoid X receptor alpha
  ribonucleotide reductase regulatory subunit M2
  ribosomal protein L35
  ribosomal protein L36
  ribosomal protein S6 kinase B2
  ring finger and CCCH-type domains 1
  ring finger and CCCH-type domains 2
  ring finger protein 4
  ring finger protein 43
  ring finger protein 8
  ring-box 1
  RIO kinase 1
  RNA polymerase I subunit H
  RNA polymerase II subunit A
  serine and arginine repetitive matrix 1
  serine/arginine repetitive matrix 2
  serpin family A member 12
  serpin family B member 7
  serpin family B member 8
  SIN3 transcription regulator family member A
  small nuclear ribonucleoprotein polypeptide A
  small nuclear ribonucleoprotein U1 subunit 70
  snail family transcriptional repressor 1
  SNW domain containing 1
  SON DNA and RNA binding protein
  Spi-1 proto-oncogene
  splicing factor proline and glutamine rich
  staufen double-stranded RNA binding protein 1
  STE20 like kinase
  striatin 4
  sulfide quinone oxidoreductase
  suppressor of cytokine signaling 3
  SURP and G-patch domain containing 2
  survival of motor neuron 1, telomeric
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
  SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
  synaptopodin
  synthesis of cytochrome C oxidase 2
  TATA-box binding protein associated factor 15
  testis expressed 101
  tet methylcytosine dioxygenase 2
  TNFAIP3 interacting protein 2
  TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase
  transcription elongation regulator 1
  transcriptional adaptor 2A
  transglutaminase 1
  transmembrane p24 trafficking protein 9
  tripartite motif containing 14
  tripartite motif containing 24
  tripartite motif containing 25
  tropomyosin 2
  tumor protein p53 binding protein 1
  tumor protein p63
  tumor susceptibility 101
  U2 small nuclear RNA auxiliary factor 2
  UBA domain containing 2
  ubiquitin conjugating enzyme E2 A
  ubiquitin conjugating enzyme E2 D1
  ubiquitin conjugating enzyme E2 I
  ubiquitin conjugating enzyme E2 M
  ubiquitin C-terminal hydrolase L3
  ubiquitin protein ligase E3 component n-recognin 5
  vascular cell adhesion molecule 1
  vir like m6A methyltransferase associated
  WW domain binding protein 4
  WW domain containing E3 ubiquitin protein ligase 2
  WW domain containing oxidoreductase
  YLP motif containing 1
  zinc finger AN1-type containing 6
  zinc finger and BTB domain containing 10
  zinc finger CCCH-type containing 11A
  zinc finger protein 746

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.