PECAM1, platelet and endothelial cell adhesion molecule 1

PECAM1, platelet and endothelial cell adhesion molecule 1

• The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. [provided by RefSeq, May 2010]

• Gene Synonyms (platelet endothelial cell adhesion molecule, CD31 antigen, platelet endothelial cell adhesion molecule-1, CD31, CD31/EndoCAM, GPIIA', PECA1, PECAM-1, endoCAM,)
• NCBI Gene ID: 5175
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A075B738
  UNIPROT ID#>>P16284
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

platelet and endothelial cell adhesion molecule 1 interacts with:

• mitogen-activated protein kinase 1
  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
  phosphoinositide-3-kinase regulatory subunit 1
  phospholipase C gamma 1
  platelet and endothelial cell adhesion molecule 1
  pre-mRNA processing factor 40 homolog A
  protein kinase C epsilon
  protein phosphatase 2 scaffold subunit Aalpha
  protein tyrosine phosphatase non-receptor type 11
  protein tyrosine phosphatase non-receptor type 6
  SRC proto-oncogene, non-receptor tyrosine kinase
  YES proto-oncogene 1, Src family tyrosine kinase

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.