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PPP2R3A, protein phosphatase 2 regulatory subunit B''alpha

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PPP2R3A, protein phosphatase 2 regulatory subunit B''alpha

  • This gene encodes one of the regulatory subunits of the protein phosphatase 2. Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the alpha subfamily of regulatory subunit B''. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Jun 2010]

  • Gene Synonyms (serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha, PP2A subunit B isoforms B72/B130, PP2A, subunit B, R3 isoform, PR130/B''alpha1 subunit, PR72/B''alpha2 subuit, protein phosphatase 2 (formerly 2A), regulatory subunit B'' (PR 72), alpha isoform and (PR 130), beta isoform, protein phosphatase 2, regulatory subunit B'', alpha, serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B, PPP2R3, PR130, PR72,)
  • NCBI Gene ID: 5523
  • Species: Homo sapiens (Human)
  • UNIPROT ID#>>Q06190
  • View the NCBI Database for this Gene »

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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