DYNC1H1, dynein cytoplasmic 1 heavy chain 1

DYNC1H1, dynein cytoplasmic 1 heavy chain 1

• Dyneins are a group of microtubule-activated ATPases that function as molecular motors. They are divided into two subgroups of axonemal and cytoplasmic dyneins. The cytoplasmic dyneins function in intracellular motility, including retrograde axonal transport, protein sorting, organelle movement, and spindle dynamics. Molecules of conventional cytoplasmic dynein are comprised of 2 heavy chain polypeptides and a number of intermediate and light chains.This gene encodes a member of the cytoplasmic dynein heavy chain family. [provided by RefSeq, Oct 2008]

• Gene Synonyms (cytoplasmic dynein 1 heavy chain 1, dynein heavy chain, cytosolic, dynein, cytoplasmic, heavy polypeptide 1, CMT2O, DHC1, DHC1a, DNCH1, DNCL, DNECL, DYHC, Dnchc1, HL-3, SMALED1, p22,)
• NCBI Gene ID: 1778
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q14204
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

dynein cytoplasmic 1 heavy chain 1 interacts with:

• AAR2 splicing factor
  actin related protein 10
  actin related protein 1A
  A-kinase anchoring protein 12
  anterior gradient 2, protein disulphide isomerase family member
  ataxin 3
  BICD cargo adaptor 2
  BICD family like cargo adaptor 1
  BICD family like cargo adaptor 2
  BRD4 interacting chromatin remodeling complex associated protein
  BTB and CNC homology 1, basic leucine zipper transcription factor 1
  calmodulin-like 3
  CAP-Gly domain containing linker protein 1
  centriolin
  centromere protein E
  coiled-coil domain containing 8
  coiled-coil domain containing 88A
  coiled-coil domain containing 88C
  COP9 signalosome subunit 5
  CREB binding protein
  cullin 3
  cullin 7
  cyclin-dependent kinase 1
  cytochrome c oxidase assembly factor COX20
  cytoskeleton associated protein 5
  decapping enzyme, scavenger
  DISC1 scaffold protein
  dual specificity phosphatase 16
  dynactin subunit 2
  dynactin subunit 4
  dynactin subunit 5
  dynamin 1 like
  dynein cytoplasmic 1 heavy chain 1
  dynein cytoplasmic 1 heavy chain 1
  dynein cytoplasmic 1 intermediate chain 1
  dynein cytoplasmic 1 intermediate chain 2
  dynein cytoplasmic 1 intermediate chain 2
  dynein cytoplasmic 1 light intermediate chain 1
  dynein cytoplasmic 1 light intermediate chain 1
  dynein cytoplasmic 1 light intermediate chain 2
  dynein light chain LC8-type 1
  dynein light chain LC8-type 1
  dynein light chain roadblock-type 1
  dynein light chain roadblock-type 1
  dynein light chain Tctex-type 1
  dynein light chain Tctex-type 3
  egl-9 family hypoxia inducible factor 3
  elongation factor Tu GTP binding domain containing 2
  elongator complex protein 1
  epidermal growth factor receptor
  epiplakin 1
  erythrocyte membrane protein band 4.1
  eukaryotic translation initiation factor 3 subunit K
  F-box and WD repeat domain containing 11
  F-box protein 7
  fibronectin 1
  filamin A
  filamin C
  forkhead box B1
  forkhead box L1
  FUS RNA binding protein
  glutamate rich WD repeat containing 1
  growth factor receptor bound protein 2
  H3 clustered histone 1
  heat shock protein 90 alpha family class A member 1
  heat shock protein family A (Hsp70) member 1A
  heat shock protein family A (Hsp70) member 8
  heterogeneous nuclear ribonucleoprotein D
  heterogeneous nuclear ribonucleoprotein L
  HEXIM P-TEFb complex subunit 1
  histone deacetylase 2
  histone deacetylase 6
  HIV-1 Tat specific factor 1
  hook microtubule tethering protein 1
  hook microtubule tethering protein 3
  huntingtin
  hydroxysteroid 17-beta dehydrogenase 10
  integrator complex subunit 5
  integrin subunit alpha 4
  interferon regulatory factor 7
  katanin catalytic subunit A1
  katanin regulatory subunit B1
  La ribonucleoprotein 7, transcriptional regulator
  leucine rich repeat kinase 2
  limb development membrane protein 1 like
  lon peptidase 1, mitochondrial
  LRR binding FLII interacting protein 1
  melatonin receptor 1B
  methylcrotonoyl-CoA carboxylase 1
  methylcrotonoyl-CoA carboxylase 2
  methylphosphate capping enzyme
  methyltransferase like 21A
  methyltransferase like 21C
  microtubule associated protein RP/EB family member 1
  minichromosome maintenance complex component 2
  muskelin 1
  MYC associated factor X
  MYC proto-oncogene, bHLH transcription factor
  nephrocystin 1
  neurotrophic receptor tyrosine kinase 1
  ninein
  ninein like
  NME/NM23 nucleoside diphosphate kinase 2
  nuclear cap binding protein subunit 1
  nuclear mitotic apparatus protein 1
  nuclear receptor coactivator 5
  nuclear receptor subfamily 2 group C member 2
  nucleoporin 133
  nudE neurodevelopment protein 1 like 1
  obscurin like cytoskeletal adaptor 1
  OFD1 centriole and centriolar satellite protein
  palmitoyl-protein thioesterase 1
  patched 1
  peptidylprolyl cis/trans isomerase, NIMA-interacting 4
  peptidylprolyl isomerase E
  peroxisomal biogenesis factor 14
  PIH1 domain containing 1
  platelet activating factor acetylhydrolase 1b regulatory subunit 1
  platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
  pleckstrin homology domain containing A4
  POC5 centriolar protein
  pre-mRNA processing factor 8
  presenilin 2
  procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
  prohibitin
  protein arginine methyltransferase 5
  protein kinase C delta
  protein phosphatase 2 regulatory subunit B''gamma
  protein phosphatase 2 scaffold subunit Aalpha
  protein phosphatase 6 catalytic subunit
  prune homolog 2 with BCH domain
  PTEN induced kinase 1
  pyruvate dehydrogenase E1 subunit alpha 1
  RAB5 interacting factor
  RAD18 E3 ubiquitin protein ligase
  RAN binding protein 9
  receptor like tyrosine kinase
  regulation of nuclear pre-mRNA domain containing 2
  replication protein A2
  rhomboid domain containing 2
  ribonucleic acid export 1
  ribosomal protein S24
  ribosomal protein S5
  ring finger protein 123
  ring finger protein 181
  ring finger protein 2
  RIO kinase 1
  RPGRIP1 like
  RUN and FYVE domain containing 1
  RuvB like AAA ATPase 2
  SAP30 binding protein
  serine and arginine rich splicing factor 9
  serine/threonine kinase 40
  SERPINE1 mRNA binding protein 1
  sirtuin 1
  sirtuin 7
  SKI proto-oncogene
  SMAD family member 2
  small nuclear ribonucleoprotein polypeptide A'
  small nuclear ribonucleoprotein polypeptides B and B1
  sodium channel and clathrin linker 1
  solute carrier family 25 member 1
  spartin
  splicing factor 3a subunit 1
  SprT-like N-terminal domain
  striatin
  striatin 4
  SUZ12 polycomb repressive complex 2 subunit
  synaptotagmin binding cytoplasmic RNA interacting protein
  synuclein alpha
  tankyrase 1 binding protein 1
  terminal nucleotidyltransferase 5A
  testin LIM domain protein
  torsin family 1 member A
  TRAF2 and NCK interacting kinase
  transcription factor CP2
  tripartite motif containing 28
  tripartite motif containing 58
  tropomyosin 2
  TSC22 domain family member 1
  tubulin, gamma 1
  tumor protein D52
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
  tyrosyl-tRNA synthetase 1
  U2 small nuclear RNA auxiliary factor 2
  ubiquitin specific peptidase 11
  ubiquitin specific peptidase 14
  ubiquitin specific peptidase 7
  unk zinc finger
  vascular cell adhesion molecule 1
  vir like m6A methyltransferase associated
  X-ray repair cross complementing 5
  Y-box binding protein 1
  Yes1 associated transcriptional regulator
  zinc finger CCCH-type containing 4
  zinc finger containing ubiquitin peptidase 1
  zinc finger protein 746

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.