GNAQ, G protein subunit alpha q

GNAQ, G protein subunit alpha q

• This locus encodes a guanine nucleotide-binding protein. The encoded protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospolipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation. A related pseudogene exists on chromosome 2.[provided by RefSeq, Nov 2010]

• Gene Synonyms (guanine nucleotide-binding protein G(q) subunit alpha, epididymis secretory sperm binding protein, guanine nucleotide binding protein (G protein), q polypeptide, guanine nucleotide-binding protein alpha-q, CMC1, G-ALPHA-q, GAQ, SWS,)
• NCBI Gene ID: 2776
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R240
  UNIPROT ID#>>P50148
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

G protein subunit alpha q interacts with:

• 5-hydroxytryptamine receptor 2A
  5-hydroxytryptamine receptor 2B
  5-hydroxytryptamine receptor 2C
  5-hydroxytryptamine receptor 6
  5'-nucleotidase, cytosolic IIIA
  A-kinase anchoring protein 13
  alcohol dehydrogenase iron containing 1
  aryl hydrocarbon receptor interacting protein
  ATP binding cassette subfamily E member 1
  autophagy related 3
  complement C1q like 4
  cyclin dependent kinase 19
  cyclin L2
  cytohesin 1
  cytohesin 2
  cytohesin 3
  dual specificity phosphatase 22
  dynein axonemal assembly factor 2
  exocyst complex component 6
  forty-two-three domain containing 1
  free fatty acid receptor 1
  free fatty acid receptor 2
  G protein subunit alpha q
  G protein subunit beta 1
  G protein subunit beta 2
  G protein subunit beta 3
  G protein subunit beta 4
  G protein subunit gamma 3
  G protein subunit gamma 4
  galanin receptor 2
  gap junction protein beta 7
  glutamate metabotropic receptor 2
  glutamate metabotropic receptor 4
  glutamate metabotropic receptor 7
  GNAS complex locus
  HCLS1 associated protein X-1
  homeobox B5
  HRas proto-oncogene, GTPase
  interferon stimulated exonuclease gene 20
  IQ motif and Sec7 domain ArfGEF 1
  kinase insert domain receptor
  kinesin associated protein 3
  lumican
  MAS related GPR family member X1
  mediator complex subunit 21
  myosin, heavy polypeptide 10, non-muscle
  nuclear FMR1 interacting protein 1
  P2Y receptor family member 8
  palmitoyl-protein thioesterase 1
  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
  phosphoinositide-3-kinase regulatory subunit 1
  phospholipase C beta 1
  phospholipase C beta 2
  pleckstrin and Sec7 domain containing
  primary cilia formation
  prostaglandin I2 receptor
  protocadherin gamma subfamily C, 3
  regulator of G protein signaling 13
  regulator of G protein signaling 16
  regulator of G protein signaling 18
  regulator of G protein signaling 2
  regulator of G protein signaling 4
  regulator of G protein signaling 5
  regulator of G protein signaling 7
  Rho guanine nucleotide exchange factor 1
  Rho guanine nucleotide exchange factor 11
  Rho guanine nucleotide exchange factor 12
  RIC8 guanine nucleotide exchange factor A
  RIC8 guanine nucleotide exchange factor B
  RIC8 guanine nucleotide exchange factor B
  ring finger protein 111
  SLC9A3 regulator 1
  solute carrier family 16 member 14
  solute carrier family 25 member 41
  sphingosine-1-phosphate receptor 2
  sprouty related EVH1 domain containing 2
  taste 2 receptor member 7
  tetratricopeptide repeat domain 1
  thromboxane A2 receptor
  thyroid stimulating hormone receptor
  tigger transposable element derived 5
  transmembrane protein 185A
  tripartite motif containing 25
  TUB bipartite transcription factor
  ubiquilin 2
  vasoactive intestinal peptide receptor 1
  WD repeat domain 36
  zinc finger protein 843

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.