CSTF2, cleavage stimulation factor subunit 2

CSTF2, cleavage stimulation factor subunit 2

• This gene encodes a nuclear protein with an RRM (RNA recognition motif) domain. The protein is a member of the cleavage stimulation factor (CSTF) complex that is involved in the 3' end cleavage and polyadenylation of pre-mRNAs. Specifically, this protein binds GU-rich elements within the 3'-untranslated region of mRNAs. [provided by RefSeq, Jul 2008]

• Gene Synonyms (cleavage stimulation factor subunit 2, CF-1 64 kDa subunit, CSTF 64 kDa subunit, betaCstF-64 variant 2, cleavage stimulation factor 64 kDa subunit, cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kD, cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, CstF-64,)
• NCBI Gene ID: 1478
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B3V096
  UNIPROT ID#>>P33240
  UNIPROT ID#>>E7EWR4
  UNIPROT ID#>>B4DUD5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

cleavage stimulation factor subunit 2 interacts with:

• abhydrolase domain containing 11
  A-kinase anchoring protein 8 like
  ankyrin repeat domain 10
  ATP23 metallopeptidase and ATP synthase assembly factor homolog
  autophagy related 16 like 1
  BAG cochaperone 6
  BRISC and BRCA1 A complex member 1
  CCR4-NOT transcription complex subunit 2
  CD2 associated protein
  CEA cell adhesion molecule 6
  cell division cycle 73
  centrosomal protein 126
  charged multivesicular body protein 2A
  cleavage and polyadenylation specific factor 1
  cleavage and polyadenylation specific factor 2
  cleavage and polyadenylation specific factor 3
  cleavage and polyadenylation specific factor 4
  cleavage and polyadenylation specific factor 6
  cleavage stimulation factor subunit 2 tau variant
  cleavage stimulation factor subunit 3
  C-terminal binding protein 2
  cullin 4B
  cullin 7
  cytochrome P450 family 1 subfamily A member 1
  cytoplasmic polyadenylation element binding protein 1
  damage specific DNA binding protein 1
  DEAD-box helicase 1
  DEAD-box helicase 19B
  elongator complex protein 1
  enoyl-CoA hydratase 1
  ergosterol biosynthesis 28 homolog
  estrogen receptor 2
  eukaryotic translation elongation factor 1 gamma
  eukaryotic translation initiation factor 4B
  EWS RNA binding protein 1
  exportin 1
  FA complementation group D2
  factor interacting with PAPOLA and CPSF1
  family with sequence similarity 168 member B
  fasciculation and elongation protein zeta 1
  guided entry of tail-anchored proteins factor 4
  H4 clustered histone 1
  haloacid dehalogenase like hydrolase domain containing 3
  hepatocyte growth factor-regulated tyrosine kinase substrate
  HEXIM P-TEFb complex subunit 1
  inhibitor of CDK, cyclin A1 interacting protein 1
  inner membrane mitochondrial protein
  integrin alpha FG-GAP repeat containing 1
  KIAA1143
  kinesin family member 21B
  limb development membrane protein 1 like
  LSM8 homolog, U6 small nuclear RNA associated
  lysine acetyltransferase 5
  MAPK interacting serine/threonine kinase 2
  methyltransferase like 15
  methyltransferase like 27
  microtubule associated protein 4
  Mov10 RISC complex RNA helicase
  MYC associated factor X
  non-POU domain containing octamer binding
  nucleoporin 153
  obscurin like cytoskeletal adaptor 1
  PALM2 and AKAP2 fusion
  PCF11 cleavage and polyadenylation factor subunit
  pleckstrin homology domain containing A4
  poly(A) binding protein cytoplasmic 1
  poly(A) polymerase alpha
  poly(A) polymerase beta
  poly(A)-specific ribonuclease
  POU class 6 homeobox 2
  PR/SET domain 6
  prefoldin subunit 6
  protein phosphatase 1 regulatory subunit 32
  RB binding protein 6, ubiquitin ligase
  regulatory factor X6
  ring finger protein 123
  RNA polymerase II subunit A
  RP2 activator of ARL3 GTPase
  saitohin
  serine and arginine repetitive matrix 1
  SH3 domain containing kinase binding protein 1
  small nuclear ribonucleoprotein U1 subunit 70
  solute carrier family 25 member 41
  solute carrier family 30 member 4
  sperm associated antigen 8
  SS18L1 subunit of BAF chromatin remodeling complex
  SSU72 homolog, RNA polymerase II CTD phosphatase
  SUB1 regulator of transcription
  symplekin
  tetratricopeptide repeat domain 27
  tetratricopeptide repeat domain 29
  TLE family member 3, transcriptional corepressor
  TNFAIP3 interacting protein 2
  trafficking from ER to golgi regulator
  TSC complex subunit 1
  ubiquilin 1
  ubiquilin 2
  ubiquilin 4
  ubiquitin specific peptidase 54
  UFM1 specific peptidase 1 (inactive)
  WW domain containing oxidoreductase
  zinc finger protein 341

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.