ELK1, ETS transcription factor ELK1

ELK1, ETS transcription factor ELK1

• This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. This gene produces multiple isoforms by using alternative translational start codons and by alternative splicing. Related pseudogenes have been identified on chromosomes 7 and 14. [provided by RefSeq, Mar 2012]

• Gene Synonyms (ETS domain-containing protein Elk-1, ELK1, ETS transcription factor, ELK1, member of ETS oncogene family, ETS-like gene 1, tyrosine kinase (ELK1) oncogene,)
• NCBI Gene ID: 2002
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P19419
  UNIPROT ID#>>A0A024R1A7
  UNIPROT ID#>>Q86SR6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ETS transcription factor ELK1 interacts with:

• docking protein 4
  E1A binding protein p300
  empty spiracles homeobox 1
  endothelial PAS domain protein 1
  ETS transcription factor ELK1
  EWS RNA binding protein 1
  F-box protein 25
  Fli-1 proto-oncogene, ETS transcription factor
  FOS like 1, AP-1 transcription factor subunit
  Fos proto-oncogene, AP-1 transcription factor subunit
  growth factor receptor bound protein 10
  growth factor receptor bound protein 2
  histone deacetylase 1
  homeobox B13
  inhibitor of DNA binding 1, HLH protein
  inhibitor of DNA binding 2
  inhibitor of DNA binding 3, HLH protein
  Kruppel like factor 4
  mitogen-activated protein kinase 1
  mitogen-activated protein kinase 10
  mitogen-activated protein kinase 11
  mitogen-activated protein kinase 3
  mitogen-activated protein kinase 8
  mitogen-activated protein kinase 9
  mitogen-activated protein kinase kinase 1
  mitogen-activated protein kinase kinase 3
  mitotic arrest deficient 2 like 2
  MOB family member 4, phocein
  peptidyl arginine deiminase 4
  phospholipase C gamma 2
  protein inhibitor of activated STAT 2
  serine/threonine kinase 16
  serum response factor
  STARD3 N-terminal like
  synuclein alpha
  TAO kinase 2
  transcriptional regulator, SIN3A (yeast)
  ubiquitin conjugating enzyme E2 I

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.