FOXA1, forkhead box A1

FOXA1, forkhead box A1

• This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. [provided by RefSeq, Jul 2008]

• Gene Synonyms (hepatocyte nuclear factor 3-alpha, HNF-3-alpha, HNF-3A, TCF-3A, forkhead box protein A1, transcription factor 3A, HNF3A, TCF3A,)
• NCBI Gene ID: 3169
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P55317
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

forkhead box A1 interacts with:

• -
  5'-3' exoribonuclease 2
  acidic residue methyltransferase 1
  actin related protein 2/3 complex subunit 2
  actin related protein 3C
  activator of basal transcription 1
  ADP ribosylation factor like GTPase 6 interacting protein 4
  alkB homolog 5, RNA demethylase
  ALX homeobox 4
  Aly/REF export factor
  anterior gradient 2, protein disulphide isomerase family member
  apoptosis antagonizing transcription factor
  ASH2 like, histone lysine methyltransferase complex subunit
  ATP/GTP binding protein like 1
  beta-1,4-glucuronyltransferase 1
  BUD23 rRNA methyltransferase and ribosome maturation factor
  chromobox 5
  chromosome 11 open reading frame 98
  chromosome 12 open reading frame 43
  cleavage and polyadenylation specific factor 7
  cms1 ribosomal small subunit homolog
  coiled-coil domain containing 137
  coiled-coil domain containing 59
  COPI coat complex subunit gamma 1
  coronin 7
  DAZ associated protein 1
  DEAD-box helicase 24
  DEAD-box helicase 31
  DEAD-box helicase 42
  DEAD-box helicase 47
  DEAD-box helicase 49
  DEAD-box helicase 51
  DEAD-box helicase 55
  DEAD-box helicase 56
  DEAH-box helicase 33
  DEAH-box helicase 37
  DEK proto-oncogene
  deoxynucleotidyltransferase terminal interacting protein 2
  destrin, actin depolymerizing factor
  deuterosome assembly protein 1
  DExD-box helicase 50
  DExD-box helicase 52
  DIMT1 rRNA methyltransferase and ribosome maturation factor
  DNA topoisomerase II alpha
  DnaJ heat shock protein family (Hsp40) member A1
  DnaJ heat shock protein family (Hsp40) member B1
  DnaJ heat shock protein family (Hsp40) member C9
  dpy-30 histone methyltransferase complex regulatory subunit
  dynein axonemal heavy chain 7
  embryonic ectoderm development
  ESF1 nucleolar pre-rRNA processing protein homolog
  eukaryotic translation initiation factor 1A Y-linked
  exosome component 1
  exosome component 10
  exosome component 2
  exosome component 3
  exosome component 4
  exosome component 6
  exosome component 9
  exportin 1
  exportin 5
  ezrin
  factor interacting with PAPOLA and CPSF1
  family with sequence similarity 207 member A
  family with sequence similarity 50 member A
  far upstream element binding protein 3
  FCF1 rRNA-processing protein
  forkhead box A3
  galectin 3
  GAR1 ribonucleoprotein
  G-patch domain containing 4
  grainyhead like transcription factor 2
  guanine monophosphate synthase
  H3 clustered histone 1
  H3.4 histone
  heterogeneous nuclear ribonucleoprotein H2
  heterogeneous nuclear ribonucleoprotein U like 1
  heterogeneous nuclear ribonucleoprotein U like 2
  histone deacetylase 7
  homeobox B9
  homeobox D13
  interferon stimulated exonuclease gene 20 like 2
  karyopherin subunit alpha 4
  kelch repeat and BTB domain containing 7
  keratin 13
  kinesin family member 23
  KRI1 homolog
  LAS1 like ribosome biogenesis factor
  LIM domain binding 1
  LIM domain binding 2
  LUC7 like
  LUC7 like 2, pre-mRNA splicing factor
  lysine acetyltransferase 7
  lysine demethylase 6A
  lysine methyltransferase 2C
  macroH2A.1 histone
  maestro heat like repeat family member 8
  mago homolog, exon junction complex subunit
  MCTS1 re-initiation and release factor
  methionyl-tRNA synthetase 1
  minichromosome maintenance complex component 3
  minichromosome maintenance complex component 7
  MISP family member 3
  mitochondrial genome maintenance exonuclease 1
  M-phase phosphoprotein 10
  M-phase phosphoprotein 6
  Mtr4 exosome RNA helicase
  mutS homolog 3
  N-alpha-acetyltransferase 40, NatD catalytic subunit
  neuroguidin
  NFKB repressing factor
  nitric oxide synthase interacting protein
  NK2 homeobox 1
  NME/NM23 nucleoside diphosphate kinase 1
  NOP10 ribonucleoprotein
  NOP16 nucleolar protein
  NOP2/Sun RNA methyltransferase 2
  NOP2/Sun RNA methyltransferase 5
  NOP53 ribosome biogenesis factor
  nuclear factor I C
  nuclear factor I X
  nuclear receptor coactivator 3
  nuclear receptor coactivator 6
  nuclear receptor interacting protein 1
  nuclear receptor subfamily 2 group F member 2
  nucleolar complex associated 4 homolog
  nucleolar pre-rRNA processing protein NIP7
  nucleolar protein 10
  nucleolar protein 11
  nucleolar protein 6
  nucleolar protein 7
  nucleolar protein 8
  nucleolar protein with MIF4G domain 1
  nucleolus and neural progenitor protein
  nucleoporin 153
  nucleus accumbens associated 1
  one cut homeobox 1
  osteoclast stimulating factor 1
  outer dense fiber of sperm tails 2
  PAK1 interacting protein 1
  partner of NOB1 homolog
  PAX interacting protein 1
  PBX homeobox 1
  PC4 and SFRS1 interacting protein 1
  peroxiredoxin 2
  PHD finger protein 2
  PHD finger protein 6
  PIN2 (TERF1) interacting telomerase inhibitor 1
  poly(A)-specific ribonuclease
  poly(ADP-ribose) polymerase 2
  POP1 homolog, ribonuclease P/MRP subunit
  pre-mRNA processing factor 3
  pre-mRNA processing factor 6
  procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
  procollagen-lysine,2-oxoglutarate 5-dioxygenase 2
  proteasome 26S subunit, non-ATPase 2
  protein arginine methyltransferase 6
  protein inhibitor of activated STAT 1
  protein phosphatase 1 catalytic subunit gamma
  PWP1 homolog, endonuclein
  RAB10, member RAS oncogene family
  Rac GTPase activating protein 1
  RALY heterogeneous nuclear ribonucleoprotein
  RB binding protein 4, chromatin remodeling factor
  RecQ like helicase
  replication protein A2
  REST corepressor 3
  REX4 homolog, 3'-5' exonuclease
  ribonuclease/angiogenin inhibitor 1
  ribosomal L24 domain containing 1
  ribosomal oxygenase 1
  ribosomal protein L10
  ribosomal protein L13a
  ribosomal protein L28
  ribosomal protein L30
  ribosomal protein L32
  ribosomal protein L5
  ribosomal protein lateral stalk subunit P0
  ribosomal protein S17
  ribosomal protein S19 binding protein 1
  ribosomal protein S27
  ribosomal protein S5
  ribosomal RNA processing 15 homolog
  ribosomal RNA processing 36
  ribosomal RNA processing 7 homolog A
  ribosomal RNA processing 9, U3 small nucleolar RNA binding protein
  ribosome production factor 1 homolog
  ring finger protein 6
  RNA binding motif protein 17
  RNA binding motif protein 19
  RNA binding motif protein 25
  RNA binding motif protein 34
  RNA binding motif protein 4
  RNA binding motif protein X-linked 2
  RNA polymerase I and III subunit C
  RNA polymerase I subunit E
  RNA polymerase I subunit G
  SATB homeobox 1
  SATB homeobox 2
  scaffold attachment factor B
  SDA1 domain containing 1
  SEC14 like lipid binding 5
  seizure related 6 homolog like 2
  septin 11
  serine and arginine rich splicing factor 12
  serine and arginine rich splicing factor 6
  serine and arginine rich splicing factor 9
  serine protease 1
  small nuclear ribonucleoprotein polypeptide A'
  small ubiquitin like modifier 1
  splicing factor 1
  splicing factor 3b subunit 4
  SPOUT domain containing methyltransferase 1
  staufen double-stranded RNA binding protein 1
  structure specific recognition protein 1
  TAR DNA binding protein
  testis expressed 10
  thioredoxin domain containing 17
  thymopoietin
  TLE family member 1, transcriptional corepressor
  TLE family member 3, transcriptional corepressor
  transcription factor AP-4
  transcription factor CP2
  transcriptional repressor GATA binding 1
  transducin beta like 3
  transformer 2 alpha homolog
  trefoil factor 1
  tripartite motif containing 33
  TSPY like 1
  TSR1 ribosome maturation factor
  tubulin gamma complex associated protein 6
  tumor protein, translationally-controlled 1
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
  ubiquitin like modifier activating enzyme 7
  ubiquitin like with PHD and ring finger domains 1
  ubiquitin specific peptidase 36
  upstream binding protein 1
  upstream binding transcription factor
  URB2 ribosome biogenesis homolog
  UTP11 small subunit processome component
  UTP14A small subunit processome component
  UTP18 small subunit processome component
  UTP20 small subunit processome component
  UTP25 small subunit processor component
  valyl-tRNA synthetase 1
  von Willebrand factor A domain containing 8
  VPS35 retromer complex component
  VRK serine/threonine kinase 1
  WD repeat domain 12
  WD repeat domain 46
  WD repeat domain 5
  WD repeat domain 75
  X-box binding protein 1
  Yes1 associated transcriptional regulator
  YLP motif containing 1
  ZFP42 zinc finger protein
  ZFP91 zinc finger protein, atypical E3 ubiquitin ligase
  zyxin

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.