KRT19, keratin 19

KRT19, keratin 19

• The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008]

• Gene Synonyms (CK19, K19, K1CS, keratin, type I cytoskeletal 19, 40-kDa keratin intermediate filament, CK-19, cytokeratin 19, keratin 19, type I, keratin, type I, 40-kd,)
• NCBI Gene ID: 3880
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P08727
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

keratin 19 interacts with:

• abl interactor 2
  ADP ribosylation factor like GTPase 4A
  agrin
  angiomotin
  angiomotin like 2
  BAG cochaperone 3
  brain expressed X-linked 2
  caspase recruitment domain family member 9
  centrosomal protein 57 like 1
  chromosome 1 open reading frame 109
  coiled-coil alpha-helical rod protein 1
  coiled-coil domain containing 146
  COP9 signalosome subunit 4
  DEPP1 autophagy regulator
  developmental pluripotency-associated 3
  DiGeorge syndrome critical region gene 6 like
  DNA polymerase lambda
  dynein light chain roadblock-type 1
  dynein light chain Tctex-type 1
  embryonic ectoderm development
  eukaryotic translation initiation factor 4A3
  eukaryotic translation initiation factor 4E family member 2
  eukaryotic translation initiation factor 4E nuclear import factor 1
  exocyst complex component 8
  family with sequence similarity 107 member A
  family with sequence similarity 124 member B
  galectin 14
  glycerate kinase
  H2A clustered histone 4
  H4 clustered histone 1
  HAUS augmin like complex subunit 1
  hepatocyte growth factor-regulated tyrosine kinase substrate
  HEXIM P-TEFb complex subunit 1
  hook microtubule tethering protein 1
  hook microtubule tethering protein 3
  IKAROS family zinc finger 3
  keratin 19
  keratin 6C
  keratin 71
  keratin 72
  keratin 74
  keratin 75
  keratin 77
  keratin 78
  keratin 79
  keratin 80
  keratin 81
  keratin 83
  keratin 85
  keratin 86
  La ribonucleoprotein 7, transcriptional regulator
  leukocyte receptor cluster member 1
  lysine demethylase 1A
  mago homolog, exon junction complex subunit
  minichromosome maintenance complex component 5
  NFKB inhibitor delta
  ninein
  nuclear receptor subfamily 2 group C member 2
  nuclear transcription factor, X-box binding 1
  pericentriolar material 1
  peripherin
  pinin, desmosome associated protein
  pleckstrin homology domain containing A5
  poly(A) specific ribonuclease subunit PAN2
  POU class 5 homeobox 1
  proteasome 20S subunit alpha 1
  protein kinase N1
  protein phosphatase 1 regulatory subunit 18
  prothymosin alpha
  protocadherin beta 12
  REST corepressor 3
  ring finger protein 123
  ring finger protein 31
  RNA polymerase I and III subunit C
  SAGA complex associated factor 29
  SFI1 centrin binding protein
  SNAP associated protein
  SPG21 abhydrolase domain containing, maspardin
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
  TBC1 domain family member 7
  TCF3 fusion partner
  TNFAIP3 interacting protein 2
  transcription factor CP2
  trichoplein keratin filament binding
  tubulin gamma 1
  tumor necrosis factor
  ubiquitin conjugating enzyme E2 A
  ubiquitin conjugating enzyme E2 I
  ubiquitin C-terminal hydrolase L5
  ubiquitin specific peptidase 32
  USH1 protein network component harmonin binding protein 1
  vascular cell adhesion molecule 1
  WD repeat domain 76
  Yes1 associated transcriptional regulator
  zinc finger protein 638

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.