PIK3CD, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta

PIK3CD, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta

• Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I PI3K found primarily in leukocytes. Like other class I PI3Ks (p110-alpha p110-beta, and p110-gamma), the encoded protein binds p85 adapter proteins and GTP-bound RAS. However, unlike the other class I PI3Ks, this protein phosphorylates itself, not p85 protein.[provided by RefSeq, Jul 2010]

• Gene Synonyms (phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform, PI3-kinase p110 subunit delta, PI3Kdelta, phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta short variant 20, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta short variant 8, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta short variant 8/20, phosphoinositide-3-kinase C, phosphoinositide-3-kinase, catalytic, delta polypeptide variant p37delta, ptdIns-3-kinase subunit p110-delta, APDS, IMD14, P110DELTA, PI3K, p110D,)
• NCBI Gene ID: 5293
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O00329
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta interacts with:

• 5',3'-nucleotidase, mitochondrial
  activating signal cointegrator 1 complex subunit 2
  amine oxidase copper containing 3
  calcium/calmodulin dependent protein kinase ID
  insulin receptor substrate 2
  leucyl-tRNA synthetase 2, mitochondrial
  MAPK regulated corepressor interacting protein 2
  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
  phosphoinositide-3-kinase regulatory subunit 1
  phosphoinositide-3-kinase regulatory subunit 2
  phosphoinositide-3-kinase regulatory subunit 3
  protein tyrosine phosphatase receptor type Z1
  RALY heterogeneous nuclear ribonucleoprotein
  TNFAIP3 interacting protein 1
  transgelin
  transportin 2
  zinc finger DHHC-type palmitoyltransferase 18
  zinc finger DHHC-type palmitoyltransferase 23

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.