ENO2, enolase 2

ENO2, enolase 2

• This gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin. A switch from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates. [provided by RefSeq, Jul 2008]

• Gene Synonyms (HEL-S-279, NSE, gamma-enolase, 2-phospho-D-glycerate hydro-lyase, 2-phospho-D-glycerate hydrolyase, enolase 2 (gamma, neuronal), epididymis secretory protein Li 279, neural enolase, neuron specific gamma enolase, neuron-specific enolase, neuronal enriched enolase, neurone-specific enolase,)
• NCBI Gene ID: 2026
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q6FHV6
  UNIPROT ID#>>P09104
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

enolase 2 interacts with:

• 3-oxoacid CoA-transferase 1
  ACD shelterin complex subunit and telomerase recruitment factor
  aldo-keto reductase family 1 member B15
  aminoadipate aminotransferase
  ankyrin repeat and SOCS box containing 5
  ankyrin repeat and SOCS box containing 9
  bMERB domain containing 1
  bromodomain containing 7
  centromere protein J
  chromosome 6 open reading frame 47
  Coenzyme A synthase
  coiled-coil-helix-coiled-coil-helix domain containing 4
  cullin 1
  cullin 2
  cullin 3
  cullin 4B
  cullin associated and neddylation dissociated 1
  EF-hand domain family member D2
  endosulfine alpha
  enolase 3
  exocyst complex component 5
  ezrin
  fatty acid binding protein 5
  FKBP prolyl isomerase 1A
  FKBP prolyl isomerase 1B
  FKBP prolyl isomerase 2
  FKBP prolyl isomerase 7
  glutamic-oxaloacetic transaminase 1
  glutathione peroxidase 4
  glutathione-disulfide reductase
  glyceraldehyde-3-phosphate dehydrogenase
  guanine monophosphate synthase
  heat shock protein family E (Hsp10) member 1
  heat shock transcription factor 1
  HEXIM P-TEFb complex subunit 1
  hexokinase 1
  histidine triad nucleotide binding protein 1
  hyaluronan binding protein 4
  hydroxysteroid 17-beta dehydrogenase 10
  interleukin 17B
  isocitrate dehydrogenase (NADP(+)) 1
  kynurenine aminotransferase 3
  La ribonucleoprotein 7, transcriptional regulator
  melatonin receptor 1A
  microtubule associated protein 4
  moesin
  N-acetyltransferase 9 (putative)
  NADH:ubiquinone oxidoreductase core subunit S7
  neurotrophic receptor tyrosine kinase 1
  NME/NM23 nucleoside diphosphate kinase 2
  NME1-NME2 readthrough
  ornithine aminotransferase
  palmitoyl-protein thioesterase 1
  peptidylprolyl isomerase B
  phosphatase and tensin homolog
  phosphoglycerate kinase 1
  phosphoglycerate mutase 1
  plastin 3
  POC1 centriolar protein A
  protection of telomeres 1
  protein phosphatase 1 catalytic subunit gamma
  protein-L-isoaspartate (D-aspartate) O-methyltransferase
  pseudouridine synthase 7
  purine nucleoside phosphorylase
  RAB1A, member RAS oncogene family
  reticulocalbin 1
  SEC31 homolog A, COPII coat complex component
  single Ig and TIR domain containing
  small ubiquitin like modifier 2
  small ubiquitin like modifier 3
  small ubiquitin like modifier 4
  snurportin 1
  ST3 beta-galactoside alpha-2,3-sialyltransferase 2
  stress induced phosphoprotein 1
  superoxide dismutase 1
  TAR DNA binding protein
  telomeric repeat binding factor 1
  TERF1 interacting nuclear factor 2
  thioredoxin
  thioredoxin reductase 2
  TNF receptor associated protein 1
  transcription factor CP2
  transferrin
  transgelin
  transgelin 2
  transgelin 3
  transketolase
  triosephosphate isomerase 1
  tubulin alpha 4a
  tumor protein D52
  ubiquitin conjugating enzyme E2 C
  ubiquitin C-terminal hydrolase L3
  WD repeat domain 1
  Yes1 associated transcriptional regulator

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.