FOXO1, forkhead box O1

FOXO1, forkhead box O1

• This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. [provided by RefSeq, Jul 2008]

• Gene Synonyms (FKH1, FKHR, FOXO1A, forkhead box protein O1, forkhead box protein O1A, forkhead, Drosophila, homolog of, in rhabdomyosarcoma,)
• NCBI Gene ID: 2308
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q12778
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

forkhead box O1 interacts with:

• autophagy related 7
  casein kinase 1 gamma 1
  COP1 E3 ubiquitin ligase
  DnaJ heat shock protein family (Hsp40) member C9
  euchromatic histone lysine methyltransferase 2
  exportin 1
  follicle stimulating hormone receptor
  forkhead box O1
  forkhead box O3B
  forkhead box O4
  forkhead box O6
  glucose-6-phosphatase catalytic subunit
  glycogen synthase kinase 3 beta
  hepatocyte nuclear factor 4 alpha
  homeobox A10
  homeobox A11
  homeobox A5
  homeobox D13
  interferon regulatory factor 3
  leucine rich pentatricopeptide repeat containing
  macrophage stimulating 1
  MDM2 proto-oncogene
  mortality factor 4 like 2
  nemo like kinase
  nuclear receptor coactivator 1
  p21 (RAC1) activated kinase 1
  paired like homeodomain 1
  peroxisome proliferator activated receptor gamma
  phosphoinositide-3-kinase regulatory subunit 3
  PML nuclear body scaffold
  protein kinase cAMP-activated catalytic subunit alpha
  RB transcriptional corepressor 1
  RecQ like helicase
  retinoic acid receptor alpha
  SATB homeobox 1
  SATB homeobox 2
  SET domain containing 7, histone lysine methyltransferase
  SET nuclear proto-oncogene
  sirtuin 1
  sirtuin 2
  sirtuin 7
  SMAD family member 3
  SMAD family member 4
  sorting nexin 17
  S-phase kinase associated protein 2
  SRC proto-oncogene, non-receptor tyrosine kinase
  STIP1 homology and U-box containing protein 1
  stratifin
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  tensin 2
  thyroid hormone receptor beta
  TSC complex subunit 2
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
  vir like m6A methyltransferase associated

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.