SFN, stratifin

SFN, stratifin

• This gene encodes a cell cycle checkpoint protein. The encoded protein binds to translation and initiation factors and functions as a regulator of mitotic translation. In response to DNA damage this protein plays a role in preventing DNA errors during mitosis. [provided by RefSeq, Aug 2017]

• Gene Synonyms (14-3-3 protein sigma, epithelial cell marker protein 1, YWHAS,)
• NCBI Gene ID: 2810
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P31947
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

stratifin interacts with:

• actin binding LIM protein 1
  ajuba LIM protein
  ankyrin repeat and sterile alpha motif domain containing 1A
  anterior gradient 2, protein disulphide isomerase family member
  BCAR1 scaffold protein, Cas family member
  BRCA1 associated protein 1
  carbohydrate sulfotransferase 1
  cell division cycle 73
  cell division cycle and apoptosis regulator 1
  cell division cycle associated 7
  cellular communication network factor 1
  chibby family member 1, beta catenin antagonist
  chromatin target of PRMT1
  cingulin
  coiled-coil domain containing 102B
  coiled-coil domain containing 125
  COP1 E3 ubiquitin ligase
  COP9 signalosome subunit 5
  COP9 signalosome subunit 6
  cytohesin 2
  DDB1 and CUL4 associated factor 7
  DEK proto-oncogene
  deltex E3 ubiquitin ligase 2
  DENN domain containing 2B
  denticleless E3 ubiquitin protein ligase homolog
  developmentally regulated GTP binding protein 1
  DNA polymerase delta 1, catalytic subunit
  early endosome antigen 1
  ERBB receptor feedback inhibitor 1
  eukaryotic translation initiation factor 3 subunit C
  eukaryotic translation initiation factor 3 subunit G
  eukaryotic translation initiation factor 3 subunit H
  eukaryotic translation initiation factor 3 subunit I
  eukaryotic translation initiation factor 5B
  exonuclease 1
  family with sequence similarity 189 member A2
  family with sequence similarity 53 member C
  family with sequence similarity 9 member B
  forkhead box O4
  G protein regulated inducer of neurite outgrowth 2
  G3BP stress granule assembly factor 1
  G3BP stress granule assembly factor 2
  gigaxonin
  glycogen synthase kinase 3 alpha
  glypican 1
  growth factor receptor bound protein 7
  H1.0 linker histone
  H1.2 linker histone, cluster member
  H1.3 linker histone, cluster member
  H2B clustered histone 3
  heat shock protein family A (Hsp70) member 5
  HECT and RLD domain containing E3 ubiquitin protein ligase 2
  heterogeneous nuclear ribonucleoprotein D
  heterogeneous nuclear ribonucleoprotein M
  heterogeneous nuclear ribonucleoprotein U
  histone deacetylase 4
  histone deacetylase 5
  histone deacetylase 7
  histone deacetylase 9
  immunoglobulin binding protein 1
  importin 5
  inhibitor of growth family member 1
  inosine monophosphate dehydrogenase 2
  insulin receptor substrate 1
  insulin receptor substrate 2
  iron-sulfur cluster assembly enzyme
  ISG15 ubiquitin like modifier
  itchy E3 ubiquitin protein ligase
  kelch domain containing 2
  keratin 1
  keratin 10
  keratin 2
  KIAA0408
  KIAA0930
  kinesin family member 23
  kinesin family member 5B
  kinesin light chain 1
  kinesin light chain 2
  KRAS proto-oncogene, GTPase
  ladinin 1
  leucine rich repeat containing 59
  leucine rich repeat kinase 2
  ligand of numb-protein X 2
  LIM and SH3 protein 1
  LIM domain 7
  lipolysis stimulated lipoprotein receptor
  LON peptidase N-terminal domain and ring finger 1
  LUC7 like 2, pre-mRNA splicing factor
  macrophage stimulating 1 receptor
  MAGE family member A1
  MAGE family member B2
  makorin ring finger protein 3
  MAPK associated protein 1
  MDM2 proto-oncogene
  MDM4 regulator of p53
  membrane associated guanylate kinase, WW and PDZ domain containing 1
  MET proto-oncogene, receptor tyrosine kinase
  microtubule affinity regulating kinase 1
  microtubule affinity regulating kinase 3
  microtubule associated protein 1B
  minichromosome maintenance complex component 2
  mitogen-activated protein kinase kinase kinase 2
  mitogen-activated protein kinase kinase kinase 20
  mitogen-activated protein kinase kinase kinase 5
  MYC binding protein 2
  myosin heavy chain 11
  myosin phosphatase Rho interacting protein
  myotubularin related protein 4
  NEDD4 like E3 ubiquitin protein ligase
  neurotrophic receptor tyrosine kinase 1
  non-POU domain containing octamer binding
  NSFL1 cofactor
  N-terminal glutamine amidase 1
  nuclear receptor subfamily 3 group C member 1
  oxysterol binding protein like 3
  p21 (RAC1) activated kinase 2
  p21 (RAC1) activated kinase 4
  paired box 9
  par-3 family cell polarity regulator
  par-3 family cell polarity regulator beta
  peptidylprolyl isomerase B
  peptidylprolyl isomerase E
  phosphatidylinositol 4-kinase beta
  phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
  phosphoglycerate kinase 1
  phospholipase D family member 6
  PIH1 domain containing 1
  plakophilin 2
  plakophilin 3
  pleckstrin homology and FYVE domain containing 2
  plectin
  polo like kinase 4
  poly(A) binding protein cytoplasmic 1
  potassium two pore domain channel subfamily K member 15
  potassium two pore domain channel subfamily K member 3
  potassium two pore domain channel subfamily K member 9
  PPFIA binding protein 1
  PPFIA binding protein 2
  pre-mRNA processing factor 8
  proteasome activator subunit 3
  protein phosphatase 1 regulatory inhibitor subunit 2
  protein phosphatase 1 regulatory subunit 3D
  protein tyrosine phosphatase non-receptor type 2
  protein tyrosine phosphatase non-receptor type 3
  PTOV1 extended AT-hook containing adaptor protein
  RAB3A interacting protein
  Rac GTPase activating protein 1
  Raf-1 proto-oncogene, serine/threonine kinase
  Ral GEF with PH domain and SH3 binding motif 2
  receptor for activated C kinase 1
  Rho GTPase activating protein 11A
  Rho GTPase activating protein 21
  Rho GTPase activating protein 32
  Rho guanine nucleotide exchange factor 16
  Rho guanine nucleotide exchange factor 17
  Rho guanine nucleotide exchange factor 5
  rhophilin Rho GTPase binding protein 2
  ribonucleic acid export 1
  ribosomal protein L10
  ribosomal protein L13
  ribosomal protein L17
  ribosomal protein L18
  ribosomal protein L23a
  ribosomal protein L24
  ribosomal protein L26
  ribosomal protein L27a
  ribosomal protein L34
  ribosomal protein L35
  ribosomal protein L38
  ribosomal protein L4
  ribosomal protein L7a
  ribosomal protein L8
  ribosomal protein S11
  ribosomal protein S13
  ribosomal protein S15a
  ribosomal protein S16
  ribosomal protein S18
  ribosomal protein S19
  ribosomal protein S2
  ribosomal protein S20
  ribosomal protein S21
  ribosomal protein S25
  ribosomal protein S3
  ribosomal protein S3A
  ribosomal protein S6
  ribosomal protein S8
  ribosomal protein S9
  ribosomal protein SA
  ring finger protein 115
  RNA binding motif protein 25
  RNA binding motif protein 39
  salvador family WW domain containing protein 1
  SAM and SH3 domain containing 1
  SAM domain, SH3 domain and nuclear localization signals 1
  serine and arginine rich splicing factor 1
  serine and arginine rich splicing factor 10
  serine and arginine rich splicing factor 2
  serine and arginine rich splicing factor 4
  serine and arginine rich splicing factor 8
  serine/arginine repetitive matrix 2
  SERPINE1 mRNA binding protein 1
  SET domain containing 1A, histone lysine methyltransferase
  SH2 domain containing 3A
  SH3 domain binding protein 4
  SHC binding and spindle associated 1
  shroom family member 3
  signal induced proliferation associated 1 like 1
  signal induced proliferation associated 1 like 3
  SIK family kinase 3
  Sin3A associated protein 18
  small nuclear ribonucleoprotein polypeptide A
  small nuclear ribonucleoprotein polypeptide F
  small nuclear ribonucleoprotein polypeptide N
  smoothelin like 2
  sorbin and SH3 domain containing 2
  S-phase kinase associated protein 1
  spire type actin nucleation factor 1
  splicing factor proline and glutamine rich
  SPT16 homolog, facilitates chromatin remodeling subunit
  STE20 like kinase
  stratifin
  SUB1 regulator of transcription
  synaptojanin 2
  TAR DNA binding protein
  TATA-box binding protein associated factor 15
  tensin 4
  thioredoxin like 1
  tight junction protein 2
  transducin beta like 3
  tripartite motif containing 25
  tripartite motif containing 28
  tripartite motif containing 32
  tripartite motif containing 62
  TSC complex subunit 2
  tumor protein p53
  tumor protein p63
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
  tyrosine kinase non receptor 1
  ubiquitin conjugating enzyme E2 R2
  ubiquitin conjugating enzyme E2 V1
  ubiquitin specific peptidase 4
  ubiquitin specific peptidase 8
  vinculin
  WEE1 G2 checkpoint kinase
  Yes1 associated transcriptional regulator
  ZFP36 ring finger protein
  zinc finger C2HC-type containing 1C
  zinc finger FYVE-type containing 19
  zinc finger protein 638

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.