BTF3, basic transcription factor 3

BTF3, basic transcription factor 3

• This gene encodes the basic transcription factor 3. This protein forms a stable complex with RNA polymerase IIB and is required for transcriptional initiation. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene has multiple pseudogenes. [provided by RefSeq, Jul 2008]

• Gene Synonyms (transcription factor BTF3, NAC-beta, RNA polymerase B transcription factor 3, nascent polypeptide-associated complex subunit beta, nascent-polypeptide-associated complex beta polypeptide, BETA-NAC, BTF3a, BTF3b, NACB,)
• NCBI Gene ID: 689
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P20290
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

basic transcription factor 3 interacts with:

• actin related protein 10
  activating signal cointegrator 1 complex subunit 3
  AF4/FMR2 family, member 1
  ATP synthase membrane subunit DAPIT
  autophagy related 16 like 1
  basic transcription factor 3
  basic transcription factor 3 like 4
  cactin, spliceosome C complex subunit
  capping actin protein of muscle Z-line subunit beta
  casein kinase 2 alpha 2
  casein kinase 2 beta
  catenin beta 1
  CCR4-NOT transcription complex subunit 1
  cell division cycle 73
  centrin 2
  centrobin, centriole duplication and spindle assembly protein
  centromere protein J
  centrosomal protein 120
  centrosomal protein 164
  centrosomal protein 43
  cysteinyl-tRNA synthetase 1
  cytidine monophosphate N-acetylneuraminic acid synthetase
  cytoskeleton associated protein 5
  dynactin subunit 1
  dynein cytoplasmic 1 intermediate chain 1
  elongation factor Tu GTP binding domain containing 2
  ERH mRNA splicing and mitosis factor
  estrogen receptor 1
  estrogen receptor 2
  eukaryotic translation initiation factor 3 subunit C
  exosome component 4
  general transcription factor IIE subunit 1
  golgi transport 1B
  H2A.X variant histone
  hypoxia inducible factor 1 subunit alpha inhibitor
  integrin alpha FG-GAP repeat containing 1
  interferon gamma inducible protein 16
  intraflagellar transport associated protein
  kinesin family member 11
  lon peptidase 1, mitochondrial
  matrin 3
  mechanistic target of rapamycin kinase
  mediator complex subunit 21
  MUS81 structure-specific endonuclease subunit
  NADH:ubiquinone oxidoreductase subunit A2
  N-alpha-acetyltransferase 40, NatD catalytic subunit
  nascent polypeptide associated complex subunit alpha
  nascent polypeptide associated complex subunit alpha 2
  N-myristoyltransferase 2
  notochord homeobox
  nuclear receptor subfamily 2 group C member 2
  nuclear transport factor 2
  p53 and DNA damage regulated 1
  pericentriolar material 1
  pinin, desmosome associated protein
  POC1 centriolar protein A
  potassium channel tetramerization domain containing 10
  programmed cell death 4
  proteasome 26S subunit, non-ATPase 12
  protein kinase N2
  protein phosphatase 2 regulatory subunit Balpha
  protein phosphatase 2 scaffold subunit Aalpha
  RAD50 interactor 1
  ribosomal protein L10
  ribosomal protein L11
  ribosomal protein L29
  ribosomal protein L35
  ring finger protein 181
  RNA binding motif protein 22
  RNA polymerase II subunit B
  RWD domain containing 4
  SEC22 homolog B, vesicle trafficking protein
  SEH1 like nucleoporin
  serine and arginine rich splicing factor 2
  SET and MYND domain containing 2
  signal recognition particle 19
  Smad nuclear interacting protein 1
  small nuclear ribonucleoprotein polypeptides B and B1
  small nuclear ribonucleoprotein U1 subunit 70
  spindle and centriole associated protein 1
  STIL centriolar assembly protein
  structural maintenance of chromosomes 6
  taxilin alpha
  taxilin beta
  timeless circadian regulator
  transmembrane protein 17
  unconventional SNARE in the ER 1
  vesicle associated membrane protein 5
  WD repeat domain 70
  WW domain containing E3 ubiquitin protein ligase 2
  zinc finger and BTB domain containing 48
  zinc finger DHHC-type palmitoyltransferase 17

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.