GNAI3, G protein subunit alpha i3

GNAI3, G protein subunit alpha i3

• Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling pathways. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes an alpha subunit and belongs to the G-alpha family. Mutation in this gene, resulting in a gly40-to-arg substitution, is associated with auriculocondylar syndrome, and shown to affect downstream targets in the G protein-coupled endothelin receptor pathway. [provided by RefSeq, Jun 2012]

• Gene Synonyms (guanine nucleotide-binding protein G(i) subunit alpha, g(i) alpha-3, guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3, guanine nucleotide-binding protein G(k) subunit alpha, 87U6, ARCND1,)
• NCBI Gene ID: 2773
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P08754
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

G protein subunit alpha i3 interacts with:

• 5-hydroxytryptamine receptor 1A
  aladin WD repeat nucleoporin
  ALG6 alpha-1,3-glucosyltransferase
  ankyrin repeat domain 13B
  apoptosis inhibitor 5
  autophagy related 16 like 1
  BAG cochaperone 3
  basic leucine zipper and W2 domains 1
  CDV3 homolog
  centrosomal protein 76
  charged multivesicular body protein 4B
  chromobox 1
  clathrin heavy chain like 1
  coiled-coil domain containing 88A
  coiled-coil domain containing 88C
  C-X-C motif chemokine receptor 2
  decapping enzyme, scavenger
  defective in cullin neddylation 1 domain containing 5
  DExD-box helicase 39B
  dual specificity phosphatase 22
  dynein light chain Tctex-type 1
  egl-9 family hypoxia inducible factor 3
  exportin 1
  G protein signaling modulator 1
  G protein signaling modulator 2
  G protein signaling modulator 3
  G protein subunit alpha i3
  G protein subunit alpha o1
  G protein subunit alpha transducin 2
  G protein subunit beta 1
  G protein subunit beta 2
  G protein subunit beta 3
  G protein subunit beta 4
  G protein subunit gamma 10
  G protein subunit gamma 11
  G protein subunit gamma 4
  G protein subunit gamma 5
  G protein subunit gamma 7
  G2 and S-phase expressed 1
  HAUS augmin-like complex, subunit 1
  HAUS augmin-like complex, subunit 4
  KRAS proto-oncogene, GTPase
  lactate dehydrogenase A
  lactate dehydrogenase B
  leucine rich repeat kinase 2
  leucyl-tRNA synthetase 1
  MAU2 sister chromatid cohesion factor
  melatonin receptor 1A
  melatonin receptor 1B
  microtubule associated monooxygenase, calponin and LIM domain containing 3
  myosin, heavy polypeptide 10, non-muscle
  myosin, heavy polypeptide 9, non-muscle
  NDC1 transmembrane nucleoporin
  neuroglobin
  neurotrophic receptor tyrosine kinase 1
  neutrophil cytosolic factor 2
  ninein
  nuclear RNA export factor 1
  nucleobindin 1
  nucleobindin 2
  oxysterol binding protein
  PHD finger protein 24
  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
  phosphogluconate dehydrogenase
  poly(A) specific ribonuclease subunit PAN2
  proteasome 20S subunit alpha 1
  proteasome 26S subunit, non-ATPase 3
  protein kinase cAMP-dependent type II regulatory subunit beta
  protein tyrosine phosphatase receptor type U
  Purkinje cell protein 2
  RAB11B, member RAS oncogene family
  Ran GTPase activating protein 1
  RAP1 GTPase activating protein
  RAS p21 protein activator 3
  RecQ protein-like 4
  regulator of G protein signaling 10
  regulator of G protein signaling 12
  regulator of G protein signaling 14
  regulator of G protein signaling 16
  regulator of G protein signaling 17
  regulator of G protein signaling 18
  regulator of G protein signaling 19
  regulator of G protein signaling 2
  regulator of G protein signaling 20
  regulator of G protein signaling 3
  regulator of G protein signaling 5
  regulator of G protein signaling 7
  retinol dehydrogenase 13
  RIC8 guanine nucleotide exchange factor A
  ring finger protein 4
  ring finger protein 6
  SRY-box transcription factor 30
  synaptopodin
  thioredoxin domain containing 5
  thyroid stimulating hormone receptor
  transcription factor CP2
  transmembrane protein 222
  tripartite motif containing 25
  tripartite motif containing 28
  tripartite motif-containing 69
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
  ubiquitin conjugating enzyme E2 A
  ubiquitin family domain containing 1
  ubiquitin specific peptidase 33
  vinculin
  Yes1 associated transcriptional regulator

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.