EGFR, epidermal growth factor receptor

EGFR, epidermal growth factor receptor

• The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. EGFR is a component of the cytokine storm which contributes to a severe form of coronavirus disease 2019 (COVID-19) resulting from infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). [provided by RefSeq, Jun 2020]

• Gene Synonyms (ERBB, ERBB1, HER1, NISBD2, PIG61, mENA, epidermal growth factor receptor, avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, epidermal growth factor receptor tyrosine kinase domain, erb-b2 receptor tyrosine kinase 1, proto-oncogene c-ErbB-1, receptor tyrosine-protein kinase erbB-1,)
• NCBI Gene ID: 1956
• Species: Homo sapiens (Human)
• UNIPROT ID#>>F2YGG7
  UNIPROT ID#>>B7Z2I3
  UNIPROT ID#>>E7BSV0
  UNIPROT ID#>>E9PFD7
  UNIPROT ID#>>Q504U8
  UNIPROT ID#>>P00533
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

epidermal growth factor receptor interacts with:

• -
  5'-3' exoribonuclease 2
  5-hydroxytryptamine receptor 3A
  5'-nucleotidase domain containing 2
  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
  AAR2 splicing factor
  actin binding LIM protein family member 3
  actin related protein 2
  activating transcription factor 7 interacting protein 2
  activator of HSP90 ATPase activity 1
  acyl-CoA thioesterase 9
  adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
  adaptor related protein complex 1 subunit gamma 2
  adaptor related protein complex 1 subunit mu 1
  adaptor related protein complex 1 subunit mu 2
  adaptor related protein complex 1 subunit sigma 2
  adaptor related protein complex 3 subunit delta 1
  adaptor related protein complex 3 subunit mu 1
  adhesion regulating molecule 1
  adipogenesis associated Mth938 domain containing
  ADP ribosylation factor guanine nucleotide exchange factor 1
  AFG3 like matrix AAA peptidase subunit 2
  AHNAK nucleoprotein
  A-kinase anchoring protein 12
  A-kinase anchoring protein 17A
  AKT interacting protein
  aladin WD repeat nucleoporin
  aminoadipate-semialdehyde dehydrogenase
  amyloid beta precursor protein binding family A member 3
  amyloid beta precursor protein binding family B member 3
  ankyrin repeat and sterile alpha motif domain containing 1A
  ankyrin repeat and sterile alpha motif domain containing 1B
  ankyrin repeat domain 13A
  ankyrin repeat domain 13B
  ankyrin repeat domain 13D
  anoctamin 5
  apoptosis inducing factor mitochondria associated 1
  apoptosis inhibitor 5
  ARFGEF family member 3
  arginine and serine rich coiled-coil 2
  arginyl-tRNA synthetase 1
  armadillo repeat containing 6
  armadillo repeat containing 8
  armadillo repeat containing X-linked 5
  aryl hydrocarbon receptor interacting protein
  ataxin 10
  ataxin 2
  ataxin 7 like 3B
  ATP binding cassette subfamily D member 3
  ATP binding cassette subfamily F member 2
  ATP synthase membrane subunit g
  ATP/GTP binding protein 1
  ATPase family AAA domain containing 1
  ATPase family AAA domain containing 3B
  ATPase H+ transporting V1 subunit H
  BAG cochaperone 2
  BAG cochaperone 5
  BAR/IMD domain containing adaptor protein 2
  Bardet-Biedl syndrome 10
  basic leucine zipper and W2 domains 1
  basic leucine zipper and W2 domains 2
  BCL2 associated transcription factor 1
  BCL2 binding component 3
  beta-1,4-galactosyltransferase 1
  bone morphogenetic protein receptor, type 1A
  BRCA2 and CDKN1A interacting protein
  BRISC and BRCA1 A complex member 2
  bromodomain PHD finger transcription factor
  BTB domain containing 18
  B-TFIID TATA-box binding protein associated factor 1
  BUB3 mitotic checkpoint protein
  cAMP-dependent protein kinase inhibitor alpha
  canopy FGF signaling regulator 3
  carboxylesterase 4A
  carboxypeptidase vitellogenic like
  caseinolytic mitochondrial matrix peptidase chaperone subunit X
  caseinolytic mitochondrial matrix peptidase proteolytic subunit
  Casitas B-lineage lymphoma
  caveolae associated protein 1
  Cbl proto-oncogene C
  CCAAT enhancer binding protein zeta
  CCCTC-binding factor like
  CCHC-type zinc finger nucleic acid binding protein
  CCR4-NOT transcription complex subunit 9
  CD109 molecule
  CD2 associated protein
  CD300 molecule like family member b
  CD82 molecule
  CDP-diacylglycerol--inositol 3-phosphatidyltransferase
  cell cycle associated protein 1
  cell cycle exit and neuronal differentiation 1
  cell division cycle 37, HSP90 cochaperone
  cell migration inducing hyaluronidase 2
  cellular inhibitor of PP2A
  centromere protein L
  centrosomal protein 104
  centrosomal protein 170
  ceramide synthase 2
  charged multivesicular body protein 4A
  chibby family member 1, beta catenin antagonist
  chromobox 2
  chromodomain helicase DNA binding protein 6
  chromosome 2 open reading frame 49
  chromosome 6 open reading frame 120
  CKLF like MARVEL transmembrane domain containing 8
  clathrin heavy chain like 1
  cms1 ribosomal small subunit homolog
  coenzyme Q8A
  coiled-coil domain containing 146
  coiled-coil domain containing 47
  coiled-coil domain containing 50
  coiled-coil domain containing 60
  coiled-coil domain containing 88A
  coiled-coil-helix-coiled-coil-helix domain containing 3
  component of oligomeric golgi complex 1
  component of oligomeric golgi complex 4
  component of oligomeric golgi complex 5
  component of oligomeric golgi complex 6
  component of oligomeric golgi complex 7
  contactin 2
  cortactin
  creatine kinase, mitochondrial 1A
  CTD small phosphatase like
  cullin 4B
  cullin associated and neddylation dissociated 2 (putative)
  cyclase associated actin cytoskeleton regulatory protein 2
  cyclin dependent kinase 13
  cysteine rich C-terminal 1
  cysteinyl-tRNA synthetase 2, mitochondrial
  cystin 1
  cytochrome c oxidase assembly factor 3
  cytokine dependent hematopoietic cell linker
  cytoskeleton associated protein 2
  cytoskeleton associated protein 4
  DEAD-box helicase 20
  DEAD-box helicase 47
  DEAD-box helicase 53
  DEAH-box helicase 16
  DEAH-box helicase 38
  debranching RNA lariats 1
  dedicator of cytokinesis 10
  dedicator of cytokinesis 4
  dehydrogenase/reductase 2
  dehydrogenase/reductase 7B
  delta 4-desaturase, sphingolipid 1
  derlin 1
  DExD/H-box helicase 60
  DIMT1 rRNA methyltransferase and ribosome maturation factor
  dipeptidase 3
  DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease
  disco interacting protein 2 homolog A
  discoidin, CUB and LCCL domain containing 2
  DIX domain containing 1
  DNA polymerase delta interacting protein 2
  DNA primase subunit 1
  DNA topoisomerase I
  DnaJ heat shock protein family (Hsp40) member A1
  DnaJ heat shock protein family (Hsp40) member A2
  DnaJ heat shock protein family (Hsp40) member A3
  DnaJ heat shock protein family (Hsp40) member B11
  DnaJ heat shock protein family (Hsp40) member B12
  DnaJ heat shock protein family (Hsp40) member C11
  DnaJ heat shock protein family (Hsp40) member C13
  DnaJ heat shock protein family (Hsp40) member C16
  DnaJ heat shock protein family (Hsp40) member C4
  DnaJ heat shock protein family (Hsp40) member C7
  docking protein 2
  docking protein 4
  docking protein 5
  docking protein 6
  dolichyl-phosphate mannosyltransferase subunit 1, catalytic
  DOP1 leucine zipper like protein A
  DOP1 leucine zipper like protein B
  dual specificity phosphatase 14
  dual specificity phosphatase 18
  dual specificity phosphatase 19
  dual specificity tyrosine phosphorylation regulated kinase 3
  dynactin subunit 2
  dynamin 1 like
  dynein axonemal assembly factor 5
  dynein axonemal heavy chain 7
  dynein cytoplasmic 1 light intermediate chain 1
  E74 like ETS transcription factor 3
  Ecm29 proteasome adaptor and scaffold
  EF-hand calcium binding domain 3
  EH domain containing 1
  EH domain containing 4
  elongator acetyltransferase complex subunit 4
  elongator complex protein 1
  EMAP like 6
  emerin
  engulfment and cell motility 2
  EPH receptor A2
  epidermal growth factor receptor
  epidermal growth factor receptor
  epidermal growth factor receptor pathway substrate 15
  epidermal growth factor receptor pathway substrate 8
  epiplakin 1
  epiregulin
  epsin 1
  ER degradation enhancing alpha-mannosidase like protein 1
  ER membrane protein complex subunit 3
  ERBB receptor feedback inhibitor 1
  erb-b2 receptor tyrosine kinase 2
  erb-b2 receptor tyrosine kinase 3
  erb-b2 receptor tyrosine kinase 4
  ERCC excision repair 1, endonuclease non-catalytic subunit
  ERCC excision repair 2, TFIIH core complex helicase subunit
  ERCC excision repair 4, endonuclease catalytic subunit
  erythrocyte membrane protein band 4.1
  erythrocyte membrane protein band 4.1 like 2
  erythropoietin receptor
  estrogen receptor 1
  estrogen receptor 2
  estrogen related receptor beta
  eukaryotic translation initiation factor 1A Y-linked
  eukaryotic translation initiation factor 2 alpha kinase 2
  eukaryotic translation initiation factor 2B subunit alpha
  eukaryotic translation initiation factor 2B subunit beta
  eukaryotic translation initiation factor 2B subunit delta
  eukaryotic translation initiation factor 2B subunit epsilon
  eukaryotic translation initiation factor 2B subunit gamma
  eukaryotic translation initiation factor 3 subunit B
  eukaryotic translation initiation factor 3 subunit F
  eukaryotic translation initiation factor 3 subunit K
  eukaryotic translation initiation factor 3 subunit M
  eukaryotic translation initiation factor 4 gamma 2
  eukaryotic translation initiation factor 4B
  eukaryotic translation initiation factor 5B
  eukaryotic translation termination factor 1
  EWS RNA binding protein 1
  exocyst complex component 3
  exocyst complex component 4
  exocyst complex component 5
  exocyst complex component 6
  exocyst complex component 6B
  exocyst complex component 7
  exocyst complex component 8
  exosome component 3
  exportin 1
  exportin 4
  exportin 5
  exportin 6
  exportin 7
  exportin for tRNA
  eyes shut homolog
  ezrin
  family with sequence similarity 126 member B
  family with sequence similarity 186 member A
  family with sequence similarity 98 member A
  farnesyl diphosphate synthase
  farnesyl-diphosphate farnesyltransferase 1
  Fas associated factor family member 2
  fatty acid desaturase 2
  fatty acyl-CoA reductase 1
  F-box protein 25
  F-box protein 6
  FER tyrosine kinase
  FES proto-oncogene, tyrosine kinase
  FGR proto-oncogene, Src family tyrosine kinase
  fibrillarin
  fibroblast growth factor receptor substrate 2
  fibronectin 1
  fibulin 7
  FKBP prolyl isomerase 4
  FKBP prolyl isomerase 8
  flap structure-specific endonuclease 1
  flotillin 2
  forkhead box O3
  Fos proto-oncogene, AP-1 transcription factor subunit
  fructosamine 3 kinase related protein
  fumarylacetoacetate hydrolase
  FUS RNA binding protein
  fyn related Src family tyrosine kinase
  G protein subunit alpha i1
  G protein subunit alpha i2
  G protein subunit alpha i3
  G protein subunit beta 2
  G protein-coupled receptor 149
  G3BP stress granule assembly factor 1
  GABA type A receptor associated protein like 2
  galectin 1
  galectin 3
  galectin 8
  gamma-aminobutyric acid type A receptor subunit alpha3
  gap junction protein beta 1
  GCN1 activator of EIF2AK4
  gem nuclear organelle associated protein 4
  gem nuclear organelle associated protein 6
  glutamate ionotropic receptor delta type subunit 1
  glutamate ionotropic receptor kainate type subunit 4
  glutamate metabotropic receptor 4
  glutamate-ammonia ligase
  glutamate-cysteine ligase modifier subunit
  glutamic-oxaloacetic transaminase 1
  glutamyl-prolyl-tRNA synthetase 1
  glutathione S-transferase kappa 1
  glutathione S-transferase pi 1
  glutathione S-transferase theta 1
  glyceraldehyde-3-phosphate dehydrogenase
  glycoprotein M6B
  glycoprotein nmb
  GNAS complex locus
  golgi associated, gamma adaptin ear containing, ARF binding protein 1
  golgi associated, gamma adaptin ear containing, ARF binding protein 2
  golgi associated, gamma adaptin ear containing, ARF binding protein 3
  golgi brefeldin A resistant guanine nucleotide exchange factor 1
  golgin B1
  G-patch domain containing 2
  G-patch domain containing 8
  granulin precursor
  GRB10 interacting GYF protein 2
  GRB2 associated binding protein 1
  GRB2 related adaptor protein 2
  GRB2-related adaptor protein 2
  growth factor receptor bound protein 10
  growth factor receptor bound protein 14
  growth factor receptor bound protein 2
  growth factor receptor bound protein 7
  H1.10 linker histone
  H2A clustered histone 1
  H2A clustered histone 18
  H2A.X variant histone
  H3.4 histone
  HCK proto-oncogene, Src family tyrosine kinase
  HEAT repeat containing 3
  HEAT repeat containing 4
  heat shock protein 90 alpha family class A member 1
  heat shock protein 90 alpha family class B member 1
  heat shock protein 90 beta family member 1
  heat shock protein family A (Hsp70) member 1A
  heat shock protein family A (Hsp70) member 1B
  heat shock protein family A (Hsp70) member 2
  heat shock protein family A (Hsp70) member 4
  heat shock protein family A (Hsp70) member 5
  heat shock protein family A (Hsp70) member 8
  heat shock protein family A (Hsp70) member 9
  heat shock protein family B (small) member 1
  HECT and RLD domain containing E3 ubiquitin protein ligase 2
  HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
  HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
  HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
  helicase, lymphoid specific
  hemoglobin subunit alpha 1
  hemoglobin subunit alpha 2
  heparin binding growth factor
  hepatocyte growth factor-regulated tyrosine kinase substrate
  hepsin
  heterogeneous nuclear ribonucleoprotein A/B
  heterogeneous nuclear ribonucleoprotein A2/B1
  heterogeneous nuclear ribonucleoprotein A3
  heterogeneous nuclear ribonucleoprotein H1
  heterogeneous nuclear ribonucleoprotein K
  heterogeneous nuclear ribonucleoprotein L
  HEXIM P-TEFb complex subunit 1
  hexokinase 1
  hexokinase 2
  hexokinase domain containing 1
  hexosaminidase D
  high mobility group AT-hook 1
  high mobility group box 1
  high mobility group box 2
  high mobility group nucleosomal binding domain 2
  histone deacetylase 1
  histone deacetylase 6
  histone deacetylase 7
  HIV-1 Tat specific factor 1
  homeobox C10
  hook microtubule tethering protein 2
  hornerin
  host cell factor C1
  HRas proto-oncogene, GTPase
  huntingtin
  huntingtin interacting protein 1
  hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
  hydroxysteroid 11-beta dehydrogenase 1
  hydroxysteroid 17-beta dehydrogenase 10
  hydroxysteroid 17-beta dehydrogenase 12
  hypoxia up-regulated 1
  IL2 inducible T cell kinase
  ILK associated serine/threonine phosphatase
  ilvB acetolactate synthase like
  immunoglobulin lambda like polypeptide 5
  importin 11
  importin 13
  importin 4
  importin 5
  importin 7
  importin 8
  importin 9
  inhibitor of growth family member 4
  inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
  inner centromere protein
  inner membrane mitochondrial protein
  inosine triphosphatase
  inositol polyphosphate phosphatase like 1
  insulin like growth factor 1 receptor
  insulin like growth factor binding protein 2
  insulin receptor substrate 1
  insulin receptor substrate 2
  insulin receptor substrate 4
  integrin subunit alpha 5
  integrin subunit beta 1
  integrin subunit beta 2
  integrin subunit beta 4
  inter-alpha-trypsin inhibitor heavy chain 2
  intercellular adhesion molecule 1
  interferon gamma inducible protein 16
  interferon induced protein with tetratricopeptide repeats 5
  interleukin 1 receptor accessory protein like 2
  interleukin 1 receptor associated kinase 1
  interleukin 13 receptor subunit alpha 2
  interleukin 5 receptor subunit alpha
  interleukin enhancer binding factor 2
  interleukin enhancer binding factor 3
  intersectin 2
  IQ motif containing GTPase activating protein 1
  IQ motif containing GTPase activating protein 3
  isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha
  isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta
  isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma
  isocitrate dehydrogenase (NADP(+)) 2
  isoleucyl-tRNA synthetase 1
  itchy E3 ubiquitin protein ligase
  Janus kinase 1
  Janus kinase 2
  Janus kinase 3
  junction plakoglobin
  Jupiter microtubule associated homolog 1
  karyopherin subunit beta 1
  katanin regulatory subunit B1 like 1
  kelch like ECH associated protein 1
  kelch repeat and BTB domain containing 7
  keratin 1
  keratin 10
  keratin 16
  keratin 17
  keratin 18
  keratin 2
  keratin 3
  keratin 5
  keratin 7
  keratin 8
  keratin 86
  keratin 9
  keratin associated protein 10-9
  keratin associated protein 15-1
  keratin associated protein 16-1
  KIAA1217
  KRAS proto-oncogene, GTPase
  L1 cell adhesion molecule
  La ribonucleoprotein 4
  ladinin 1
  lamin A/C
  laminin subunit beta 3
  LanC like 1
  LanC like 2
  LDL receptor related protein 1
  LDL receptor related protein 8
  lebercilin LCA5 like
  leucine rich pentatricopeptide repeat containing
  leucine rich repeat and sterile alpha motif containing 1
  leucine rich repeat containing 40
  leucine rich repeat kinase 1
  leucine rich repeat transmembrane neuronal 4
  leucine rich repeats and immunoglobulin like domains 1
  leucine rich repeats and immunoglobulin like domains 2
  leucine rich repeats and immunoglobulin like domains 3
  leucine rich repeats and WD repeat domain containing 1
  leukocyte receptor tyrosine kinase
  LIM domain and actin binding 1
  limb development membrane protein 1
  linker for activation of T cells
  lipolysis stimulated lipoprotein receptor
  listerin E3 ubiquitin protein ligase 1
  lon peptidase 1, mitochondrial
  LSM14A mRNA processing body assembly factor
  LUC7 like 3 pre-mRNA splicing factor
  lymphocyte cytosolic protein 2
  LYN proto-oncogene, Src family tyrosine kinase
  lysosomal associated membrane protein 1
  macrophage migration inhibitory factor
  MAGE family member D2
  major histocompatibility complex, class I, A
  major histocompatibility complex, class I, B
  malate dehydrogenase 1
  MAS1 proto-oncogene, G protein-coupled receptor
  matrin 3
  MDM2 binding protein
  mechanistic target of rapamycin kinase
  megakaryocyte-associated tyrosine kinase
  MET proto-oncogene, receptor tyrosine kinase
  metadherin
  methionyl-tRNA synthetase 1
  MHC class I polypeptide-related sequence B
  microfibril associated protein 1
  microsomal glutathione S-transferase 1
  microsomal glutathione S-transferase 2
  microtubule associated protein 1 light chain 3 alpha
  microtubule associated protein 4
  microtubule associated protein tau
  microtubule associated serine/threonine kinase 1
  microtubule associated serine/threonine kinase 2
  MIER1 transcriptional regulator
  minichromosome maintenance complex component 3
  minichromosome maintenance complex component 4
  minichromosome maintenance complex component 6
  mitochondria localized glutamic acid rich protein
  mitochondrial contact site and cristae organizing system subunit 10
  mitochondrial inner membrane protein MPV17
  mitochondrial pyruvate carrier 2
  mitochondrial ribosomal protein L10
  mitochondrial ribosomal protein L43
  mitochondrial ribosomal protein L9
  mitochondrial ribosome associated GTPase 1
  mitochondrial rRNA methyltransferase 3
  mitochondrially encoded cytochrome c oxidase II
  mitogen-activated protein kinase 1
  mitogen-activated protein kinase 15
  mitogen-activated protein kinase 8
  mitogen-activated protein kinase 8 interacting protein 1
  mitogen-activated protein kinase 8 interacting protein 2
  mitogen-activated protein kinase 9
  mitogen-activated protein kinase kinase 1
  mitogen-activated protein kinase kinase 2
  mitogen-activated protein kinase kinase 3
  mitogen-activated protein kinase kinase 4
  mitogen-activated protein kinase kinase kinase 12
  mitogen-activated protein kinase kinase kinase 14
  mitogen-activated protein kinase kinase kinase 3
  mitogen-activated protein kinase kinase kinase kinase 1
  mitogen-activated protein kinase kinase kinase kinase 5
  MLX interacting protein like
  MMS19 homolog, cytosolic iron-sulfur assembly component
  MOB family member 4, phocein
  MON2 homolog, regulator of endosome-to-Golgi trafficking
  MRT4 homolog, ribosome maturation factor
  mucin 1, cell surface associated
  mucin 16, cell surface associated
  mucin 4, cell surface associated
  MYC binding protein
  MYC binding protein 2
  myelin protein zero like 2
  myosin heavy chain 9
  myosin IB
  myosin IC
  myosin ID
  myosin IXA
  myotubularin related protein 8
  NAD synthetase 1
  NADH:ubiquinone oxidoreductase core subunit S1
  NADH:ubiquinone oxidoreductase core subunit S3
  NADH:ubiquinone oxidoreductase subunit A9
  N-alpha-acetyltransferase 10, NatA catalytic subunit
  NCK adaptor protein 1
  NCK adaptor protein 2
  necdin, MAGE family member
  NEDD4 E3 ubiquitin protein ligase
  Nedd4 family interacting protein 1
  Nedd4 family interacting protein 2
  nephrocystin 4
  N-ethylmaleimide sensitive factor, vesicle fusing ATPase
  neural cell adhesion molecule 1
  neural EGFL like 1
  neuregulin 1
  neurobeachin like 2
  neurochondrin
  neurofibromin 1
  neurofibromin 2
  neurotrophic receptor tyrosine kinase 1
  neurotrophic receptor tyrosine kinase 2
  N-glycanase 1
  niban apoptosis regulator 2
  nicalin
  NIMA related kinase 8
  nitric oxide synthase interacting protein
  NLR family pyrin domain containing 10
  non-SMC condensin I complex subunit G
  non-SMC condensin I complex subunit H
  non-SMC condensin II complex subunit G2
  non-SMC condensin II complex subunit H2
  NOP2/Sun RNA methyltransferase 2
  NOP2/Sun RNA methyltransferase 5
  NRAS proto-oncogene, GTPase
  nth like DNA glycosylase 1
  nuclear casein kinase and cyclin dependent kinase substrate 1
  nuclear receptor subfamily 3 group C member 1
  nuclear RNA export factor 2
  nucleic acid binding protein 2
  nucleolar protein 6
  nucleolin
  nucleophosmin 1
  nucleoporin 153
  nucleoporin 85
  nucleoporin 93
  nucleoside-triphosphatase, cancer-related
  nucleotide binding protein 2
  NUMB endocytic adaptor protein
  NUMB like endocytic adaptor protein
  olfactomedin 1
  olfactory receptor family 2 subfamily F member 2
  olfactory receptor family 2 subfamily W member 3
  oncostatin M receptor
  OPA1 mitochondrial dynamin like GTPase
  origin recognition complex subunit 5
  ornithine aminotransferase
  ornithine decarboxylase antizyme 1
  OS9 endoplasmic reticulum lectin
  OTU deubiquitinase 7B
  OTU deubiquitinase with linear linkage specificity like
  outer dense fiber of sperm tails 3 like 2
  oxidative stress responsive kinase 1
  oxysterol binding protein
  p21 (RAC1) activated kinase 1
  p21 (RAC1) activated kinase 4
  PAGE family member 3
  pantothenate kinase 4 (inactive)
  paraoxonase 2
  paraspeckle component 1
  parkin RBR E3 ubiquitin protein ligase
  partner of NOB1 homolog
  patched 1
  PDGFA associated protein 1
  PDS5 cohesin associated factor A
  pecanex 1
  pelota mRNA surveillance and ribosome rescue factor
  peptidylprolyl cis/trans isomerase, NIMA-interacting 4
  peptidylprolyl isomerase B
  peroxiredoxin 1
  peroxisomal biogenesis factor 19
  peroxisome proliferator activated receptor gamma
  phenylalanyl-tRNA synthetase subunit alpha
  phosphatase and tensin homolog
  phosphatidylinositol binding clathrin assembly protein
  phosphatidylinositol glycan anchor biosynthesis class S
  phosphatidylinositol transfer protein alpha
  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
  phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha
  phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
  phosphatidylinositol-4-phosphate 5-kinase type 1 alpha
  phosphodiesterase 1C
  phosphofructokinase, liver type
  phosphofructokinase, muscle
  phosphofructokinase, platelet
  phosphoglycerate dehydrogenase
  phosphoinositide-3-kinase regulatory subunit 1
  phosphoinositide-3-kinase regulatory subunit 2
  phosphoinositide-3-kinase regulatory subunit 3
  phospholipase A2 activating protein
  phospholipase A2 group IIA
  phospholipase C gamma 1
  phospholipase C gamma 2
  phospholipase D family member 3
  phospholipase D1
  phospholipase D2
  phospholipid scramblase 1
  phosphomannomutase 2
  phosphotyrosine interaction domain containing 1
  Pim-1 proto-oncogene, serine/threonine kinase
  plakophilin 3
  plasmalemma vesicle associated protein
  plastin 3
  platelet derived growth factor receptor alpha
  platelet derived growth factor receptor beta
  pleckstrin 2
  pleckstrin homology domain containing A7
  pleckstrin homology like domain family A member 1
  plectin
  PML nuclear body scaffold
  polo like kinase 1
  potassium voltage-gated channel subfamily Q member 1
  PPARG coactivator 1 alpha
  prickle planar cell polarity protein 1
  progesterone receptor membrane component 1
  programmed cell death 6 interacting protein
  proliferating cell nuclear antigen
  proline rich 14
  proline rich mitotic checkpoint control factor
  prolyl 3-hydroxylase 1
  prolyl 4-hydroxylase subunit beta
  prostaglandin D2 synthase
  prostaglandin E synthase 3
  proteasome 20S subunit alpha 3
  proteasome 20S subunit alpha 4
  proteasome 20S subunit alpha 7
  proteasome 26S subunit, non-ATPase 1
  proteasome 26S subunit, non-ATPase 2
  proteasome 26S subunit, non-ATPase 4
  protein arginine methyltransferase 3
  protein disulfide isomerase family A member 3
  protein kinase AMP-activated catalytic subunit alpha 1
  protein kinase AMP-activated non-catalytic subunit gamma 1
  protein kinase C alpha
  protein kinase C beta
  protein kinase C delta
  protein kinase C epsilon
  protein kinase C zeta
  protein kinase cAMP-activated catalytic subunit alpha
  protein kinase cAMP-dependent type I regulatory subunit alpha
  protein kinase cAMP-dependent type I regulatory subunit beta
  protein kinase D1
  protein kinase, DNA-activated, catalytic subunit
  protein phosphatase 2 regulatory subunit Balpha
  protein phosphatase 2 regulatory subunit B''alpha
  protein phosphatase 2 regulatory subunit B'epsilon
  protein phosphatase 2 regulatory subunit B'gamma
  protein phosphatase 2 scaffold subunit Aalpha
  protein phosphatase 2 scaffold subunit Abeta
  protein phosphatase 3 catalytic subunit beta
  protein phosphatase 5 catalytic subunit
  protein phosphatase 6 catalytic subunit
  protein phosphatase 6 regulatory subunit 1
  protein phosphatase, Mg2+/Mn2+ dependent 1A
  protein phosphatase, Mg2+/Mn2+ dependent 1B
  protein phosphatase, Mg2+/Mn2+ dependent 1F
  protein tyrosine kinase 2
  protein tyrosine kinase 2 beta
  protein tyrosine kinase 6
  protein tyrosine phosphatase non-receptor type 1
  protein tyrosine phosphatase non-receptor type 11
  protein tyrosine phosphatase non-receptor type 12
  protein tyrosine phosphatase non-receptor type 18
  protein tyrosine phosphatase non-receptor type 2
  protein tyrosine phosphatase non-receptor type 20
  protein tyrosine phosphatase non-receptor type 22
  protein tyrosine phosphatase non-receptor type 23
  protein tyrosine phosphatase non-receptor type 6
  protein tyrosine phosphatase non-receptor type 7
  protein tyrosine phosphatase receptor type A
  protein tyrosine phosphatase receptor type B
  protein tyrosine phosphatase receptor type D
  protein tyrosine phosphatase receptor type F
  protein tyrosine phosphatase receptor type H
  protein tyrosine phosphatase receptor type J
  protein tyrosine phosphatase receptor type K
  protein tyrosine phosphatase receptor type R
  protein tyrosine phosphatase receptor type S
  protein tyrosine phosphatase receptor type T
  protein tyrosine phosphatase receptor type U
  protocadherin beta 11
  protocadherin gamma subfamily A, 3
  pseudouridine synthase 1
  pumilio RNA binding family member 1
  pyridoxal dependent decarboxylase domain containing 1
  pyrroline-5-carboxylate reductase 2
  pyruvate carboxylase
  pyruvate dehydrogenase kinase 1
  pyruvate dehydrogenase kinase 3
  pyruvate dehyrogenase phosphatase catalytic subunit 1
  RAB guanine nucleotide exchange factor 1
  RAB18, member RAS oncogene family
  RAB1A, member RAS oncogene family
  RAB31, member RAS oncogene family
  RAB3A, member RAS oncogene family
  RAB5A, member RAS oncogene family
  Raf-1 proto-oncogene, serine/threonine kinase
  RAN binding protein 1
  Ran GTPase activating protein 1
  Rap guanine nucleotide exchange factor 1
  Rap1 GTPase-GDP dissociation stimulator 1
  Ras and Rab interactor 1
  Ras and Rab interactor 2
  RAS p21 protein activator 1
  RAS p21 protein activator 4B
  RasGEF domain family member 1B
  receptor accessory protein 4
  receptor interacting serine/threonine kinase 1
  regulation of nuclear pre-mRNA domain containing 1A
  regulator of chromosome condensation 2
  regulator of G protein signaling 16
  regulator of G protein signaling 2
  regulator of G protein signaling 4
  replication factor C subunit 3
  replication factor C subunit 4
  replication factor C subunit 5
  replication protein A1
  replication protein A2
  replication protein A3
  ret proto-oncogene
  retention in endoplasmic reticulum sorting receptor 1
  reticulocalbin 2
  Rho GTPase activating protein 29
  Rho GTPase activating protein 32
  Rho guanine nucleotide exchange factor 12
  Rho guanine nucleotide exchange factor 5
  Rho guanine nucleotide exchange factor 7
  Rho/Rac guanine nucleotide exchange factor 2
  rhomboid 5 homolog 2
  ribophorin I
  ribosomal protein L14
  ribosomal protein L17
  ribosomal protein L22
  ribosomal protein L23
  ribosomal protein L3
  ribosomal protein L38
  ribosomal protein L4
  ribosomal protein L6
  ribosomal protein L7
  ribosomal protein lateral stalk subunit P2
  ribosomal protein S15
  ribosomal protein S15a
  ribosomal protein S20
  ribosomal protein S27
  ribosomal protein S3
  ribosomal protein S6 kinase A3
  ribosome production factor 1 homolog
  ring finger protein 115
  ring finger protein 125
  ring finger protein 126
  ring finger protein 144A
  ring finger protein 213
  ring finger protein, LIM domain interacting
  RIO kinase 1
  RIO kinase 2
  RNA binding motif protein 10
  RNA binding motif protein 25
  RNA binding motif protein 39
  RNA binding motif protein 41
  RNA polymerase II subunit A
  roundabout guidance receptor 4
  RRAD, Ras related glycolysis inhibitor and calcium channel regulator
  rubicon autophagy regulator
  RUN and SH3 domain containing 2
  RUN domain containing 3B
  RuvB like AAA ATPase 2
  RWD domain containing 1
  S100 calcium binding protein A10
  S100 calcium binding protein A4
  S100 calcium binding protein A7
  S100 calcium binding protein A9
  SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
  SAMM50 sorting and assembly machinery component
  schlafen family member 11
  SCY1 like pseudokinase 1
  SCY1 like pseudokinase 2
  sec1 family domain containing 1
  SEC13 homolog, nuclear pore and COPII coat complex component
  SEC16 homolog A, endoplasmic reticulum export factor
  SEC61 translocon subunit alpha 1
  SEC61 translocon subunit beta
  secretoglobin family 1D member 4
  secretory carrier membrane protein 1
  secretory carrier membrane protein 3
  SEL1L adaptor subunit of ERAD E3 ubiquitin ligase
  selenoprotein P
  senataxin
  serine active site containing 1
  serine and arginine repetitive matrix 1
  serine and arginine rich splicing factor 11
  serine and arginine rich splicing factor 2
  serine palmitoyltransferase long chain base subunit 1
  serine palmitoyltransferase long chain base subunit 2
  serine/arginine repetitive matrix 2
  serine/arginine repetitive matrix 4
  serine/threonine kinase 26
  serine/threonine kinase receptor associated protein
  serine/threonine/tyrosine interacting protein
  serpin family B member 12
  serpin family B member 4
  SERPINE1 mRNA binding protein 1
  SERTA domain containing 4
  serum amyloid A like 1
  sestrin 2
  SH2 domain containing 1A
  SH2 domain containing 2A
  SH2 domain containing 3A
  SH2 domain containing 3C
  SH2B adaptor protein 1
  SH2B adaptor protein 3
  SH3 and multiple ankyrin repeat domains 2
  SH3 domain binding glutamate rich protein like
  SH3 domain binding glutamate rich protein like 3
  SH3 domain containing GRB2 like 2, endophilin A1
  SH3 domain containing GRB2 like 3, endophilin A3
  SH3 domain containing kinase binding protein 1
  SHC adaptor protein 1
  SHC adaptor protein 2
  SHC adaptor protein 3
  SHC adaptor protein 4
  sideroflexin 3
  signal peptidase complex subunit 2
  signal sequence receptor subunit 4
  signal transducer and activator of transcription 1
  signal transducer and activator of transcription 2
  signal transducer and activator of transcription 3
  signal transducer and activator of transcription 5A
  signal transducer and activator of transcription 5B
  signal transducing adaptor family member 2
  signal transducing adaptor molecule 2
  single stranded DNA binding protein 1
  Ski2 like RNA helicase
  SLC9A3 regulator 1
  slingshot protein phosphatase 1
  SLIT and NTRK like family member 3
  SMAD specific E3 ubiquitin protein ligase 2
  small G protein signaling modulator 2
  small integral membrane protein 5
  small nuclear ribonucleoprotein D1 polypeptide
  small nuclear ribonucleoprotein D2 polypeptide
  small nuclear ribonucleoprotein polypeptide A'
  small nuclear ribonucleoprotein polypeptide F
  small proline rich protein 1A
  small RNA binding exonuclease protection factor La
  SMG1 nonsense mediated mRNA decay associated PI3K related kinase
  smoothelin
  smoothelin like 1
  solute carrier family 1 member 5
  solute carrier family 12 member 2
  solute carrier family 13 member 5
  solute carrier family 25 member 13
  solute carrier family 3 member 1
  solute carrier family 3 member 2
  solute carrier family 39 member 11
  solute carrier family 39 member 7
  solute carrier family 45 member 2
  solute carrier family 45 member 4
  solute carrier family 7 member 11
  solute carrier family 7 member 5
  solute carrier organic anion transporter family member 3A1
  sorbin and SH3 domain containing 2
  sorting nexin 1
  sorting nexin 2
  sorting nexin 29
  sorting nexin 4
  sorting nexin 6
  sorting nexin 9
  SOS Ras/Rac guanine nucleotide exchange factor 1
  SOS Ras/Rho guanine nucleotide exchange factor 2
  SPARC like 1
  spectrin alpha, non-erythrocytic 1
  spen family transcriptional repressor
  sperm associated antigen 7
  sperm associated antigen 8
  spermatogenesis and centriole associated 1 like
  sperm-tail PG-rich repeat containing 4
  sphingosine-1-phosphate lyase 1
  spindlin interactor and repressor of chromatin binding
  spleen associated tyrosine kinase
  splicing factor proline and glutamine rich
  SPT5 homolog, DSIF elongation factor subunit
  Src like adaptor
  Src like adaptor 2
  SRC proto-oncogene, non-receptor tyrosine kinase
  SRP receptor subunit alpha
  SRP receptor subunit beta
  ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
  stearoyl-CoA desaturase
  STIL centriolar assembly protein
  STIP1 homology and U-box containing protein 1
  stomatin
  stratifin
  stress induced phosphoprotein 1
  stromal cell derived factor 2
  stromal cell derived factor 2 like 1
  structural maintenance of chromosomes 1A
  structural maintenance of chromosomes 2
  structural maintenance of chromosomes 3
  structure specific recognition protein 1
  STT3 oligosaccharyltransferase complex catalytic subunit A
  SUB1 regulator of transcription
  succinate-CoA ligase ADP-forming subunit beta
  sulfotransferase family 1A member 1
  suppressor of cytokine signaling 1
  suppressor of cytokine signaling 3
  suppressor of cytokine signaling 4
  suppressor of cytokine signaling 5
  suppressor of cytokine signaling 6
  suppressor of cytokine signaling 7
  SURP and G-patch domain containing 2
  sushi domain containing 1
  SWT1 RNA endoribonuclease homolog
  synaptic Ras GTPase activating protein 1 homolog (rat)
  synaptotagmin 17
  synuclein alpha
  T cell immune regulator 1, ATPase H+ transporting V0 subunit a3
  talin 1
  TANK binding kinase 1
  target of myb1 like 1 membrane trafficking protein
  TATA-box binding protein associated factor 4
  t-complex 1
  tektin 2
  TELO2 interacting protein 1
  TELO2 interacting protein 2
  telomere maintenance 2
  tenascin C
  tensin 3
  tensin 4
  testis and ovary specific PAZ domain containing 1
  tetratricopeptide repeat domain 27
  tetratricopeptide repeat domain 37
  TGF-beta activated kinase 1 (MAP3K7) binding protein 1
  THADA armadillo repeat containing
  thimet oligopeptidase 1
  thioesterase superfamily member 6
  thioredoxin
  threonyl-tRNA synthetase 1
  threonyl-tRNA synthetase 2, mitochondrial
  thyrotropin releasing hormone degrading enzyme
  tight junction protein 1
  titin
  TNF receptor associated factor 2
  TNF receptor associated factor 4
  TNF receptor superfamily member 10b
  TNF receptor superfamily member 11a
  TNF receptor superfamily member 1A
  toll like receptor 2
  torsin 1A interacting protein 1
  torsin family 4 member A
  TRAF2 and NCK interacting kinase
  TRAF3 interacting protein 1
  trafficking protein particle complex 3
  trafficking protein particle complex 5
  TRAF-type zinc finger domain containing 1
  trans-2,3-enoyl-CoA reductase
  transcription factor AP-2 alpha
  transducin beta like 3
  transferrin receptor
  transformer 2 beta homolog
  transforming growth factor alpha
  transforming growth factor beta regulator 4
  transient receptor potential cation channel subfamily M member 3
  transient receptor potential cation channel subfamily V member 1
  translocase of inner mitochondrial membrane 23
  translocase of inner mitochondrial membrane 50
  translocase of outer mitochondrial membrane 22
  translocase of outer mitochondrial membrane 70
  transmembrane 9 superfamily member 3
  transmembrane and coiled-coil domains 3
  transmembrane BAX inhibitor motif containing 1
  transmembrane protein 159
  transmembrane protein 25
  transmembrane protein 267
  transmembrane protein 43
  transmembrane protein 97
  transportin 1
  transportin 2
  transportin 3
  treacle ribosome biogenesis factor 1
  triosephosphate isomerase 1
  tripartite motif containing 28
  tripartite motif family like 2
  tRNA methyltransferase 1 like
  tRNA methyltransferase 10C, mitochondrial RNase P subunit
  tRNA methyltransferase 2 homolog A
  tropomyosin 1
  tropomyosin 3
  tropomyosin 4
  Tu translation elongation factor, mitochondrial
  tubulin alpha 1a
  tubulin alpha 4a
  tubulin beta 2A class IIa
  tubulin beta 3 class III
  tubulin beta 4A class IVa
  tubulin beta 4B class IVb
  tubulin beta 6 class V
  tubulin beta class I
  tubulin gamma 1
  tubulin gamma complex associated protein 2
  tumor protein p53
  tumor susceptibility 101
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
  tyrosine kinase non receptor 2
  tyrosyl-tRNA synthetase 1
  U2 small nuclear RNA auxiliary factor 2
  ubiquinol-cytochrome c reductase core protein 2
  ubiquitin associated and SH3 domain containing A
  ubiquitin associated and SH3 domain containing B
  ubiquitin associated protein 2 like
  ubiquitin B
  ubiquitin C
  ubiquitin conjugating enzyme E2 G2
  ubiquitin conjugating enzyme E2 J2
  ubiquitin conjugating enzyme E2 S
  ubiquitin conjugating enzyme E2 V2
  ubiquitin C-terminal hydrolase L1
  ubiquitin like modifier activating enzyme 2
  ubiquitin protein ligase E3 component n-recognin 4
  ubiquitin protein ligase E3C
  ubiquitin specific peptidase 2
  ubiquitin specific peptidase 31
  ubiquitin specific peptidase 34
  ubiquitin specific peptidase 8
  ubiquitin specific peptidase 8
  ubiquitin specific peptidase 9 X-linked
  UDP-glucose glycoprotein glucosyltransferase 1
  UFM1 specific ligase 1
  unc-80 homolog, NALCN channel complex subunit
  uridine monophosphate synthetase
  uridine phosphorylase 1
  uridine-cytidine kinase 2
  uroporphyrinogen decarboxylase
  UTP15 small subunit processome component
  VAC14 component of PIKFYVE complex
  vacuolar protein sorting 13 homolog A
  vacuolar protein sorting 4 homolog B
  valyl-tRNA synthetase 1
  VAMP associated protein A
  vav guanine nucleotide exchange factor 1
  vav guanine nucleotide exchange factor 2
  vav guanine nucleotide exchange factor 3
  vimentin
  vir like m6A methyltransferase associated
  voltage dependent anion channel 1
  VPS33B late endosome and lysosome associated
  VRK serine/threonine kinase 1
  WASP actin nucleation promoting factor
  WASP family member 3
  WASP like actin nucleation promoting factor
  WD repeat domain 26
  WD repeat domain 6
  WD repeat domain, phosphoinositide interacting 2
  WW and C2 domain containing 2
  WW domain binding protein 2
  WW domain containing E3 ubiquitin protein ligase 1
  X-ray radiation resistance associated 1
  X-ray repair cross complementing 5
  X-ray repair cross complementing 6
  ybeY metalloendoribonuclease
  Y-box binding protein 1
  YES proto-oncogene 1, Src family tyrosine kinase
  Yes1 associated transcriptional regulator
  YTH N6-methyladenosine RNA binding protein 1
  zeta chain of T cell receptor associated protein kinase 70
  zinc finger and BTB domain containing 14
  zinc finger and BTB domain containing 22
  zinc finger CCCH-type containing 4
  zinc finger CCCH-type containing, antiviral 1
  zinc finger CCHC-type containing 18
  zinc finger FYVE-type containing 21
  zinc finger FYVE-type containing 28
  zinc finger MYM-type containing 4
  zinc finger protein 114
  zinc finger protein 516
  zinc finger protein 573
  zinc finger RNA binding protein
  zinc finger ZZ-type containing 3
  ZPR1 zinc finger
  zw10 kinetochore protein

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.